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    Research 31–60 of 1000+

    1. Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics Scientific Reports · 2022
    2. Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion 2011 · 30 citations
    3. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    4. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2 Bioorganic & Medicinal Chemistry Letters · 2004 · 9 citations
    5. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    6. A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation bioRxiv (Cold Spring Harbor Laboratory) · 2022
    7. Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1 Bioorganic & Medicinal Chemistry · 2001 · 12 citations
    8. Longitudinal clinical course in patients with 5α-reductase type 2 deficiency treated with testosterone and dihydrotestosterone during infancy and puberty Endocrine journal · 2022
    9. Evidence of Heterogeneity and Quantitative Differences of the Type 1 5α-Reductase Expression in Cultured Human Skin Cells – Evidence of its Presence in Melanocytes Journal of Investigative Dermatology · 1998 · 83 citations
    10. In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride Journal of Pharmaceutical Sciences · 1996 · 29 citations
    11. The hair growth promoting effect of Sophora flavescens extract and its molecular regulation Journal of Dermatological Science · 2002 · 75 citations
    12. Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1 Bioorganic & medicinal chemistry · 2018 · 3 citations
    13. Evaluating Antiinflammatory and Antiandrogenic Effects of Garden Cress (Lepidium sativum L.) in HaCaT cells Records of Natural Products · 2018 · 5 citations
    14. Discovery and Clinical Development of Dutasteride, a Potent Dual 5α- Reductase Inhibitor Current topics in medicinal chemistry · 2006 · 58 citations
    15. A Natural Inhibitor, 1′S-1′-Acetoxychavicol Acetate, Against Testosterone-Induced Alopecia via NADPH Oxidase Regulation Molecules · 2025
    16. Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism 2001 · 115 citations
    17. An Exploratory In Vivo Study on the Effect of Annurca Apple Extract on Hair Growth in Mice Current Issues in Molecular Biology · 2022 · 1 citations
    18. Role of 5α-reductase inhibitors in androgen-stimulated skin disorders. PubMed · 2013 · 3 citations
    19. The Biomolecular Effects of Finasteride on Male Rat Brain during Administration and after Discontinuation The World Journal of Men s Health · 2025
    20. PNU 157706, a novel dual type I and II5α-reductase inhibitor The Journal of Steroid Biochemistry and Molecular Biology · 1998 · 42 citations
    21. On the effects of a plant extract of Orthosiphon stamineus on sebum-related skin imperfections International Journal of Cosmetic Science · 2010 · 17 citations
    22. An Integrated Approach to Develop Innovative, Sustainable, and Effective Cosmetic Ingredients: The Case Report of Fatty-Acids-Enriched Wild Strawberry Waste Extract Applied Sciences · 2024
    23. Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation Psychoneuroendocrinology · 2019 · 12 citations
    24. Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2004
    25. Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay BMC Complementary and Alternative Medicine · 2015 · 17 citations
    26. Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions Bioorganic & Medicinal Chemistry Letters · 1998 · 14 citations
    27. Isozyme phenotypes of polyoma virus tumors in mice. PubMed · 1983 · 5 citations
    28. Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase Bioorganic & Medicinal Chemistry · 1997 · 5 citations
    29. Phenyl Propanoid 1’s-1′-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting Nadph Oxidase 2025
    30. Inhibitors of 5α -Reductase Type I in LNCaP Cells from the Roots of Angelica koreana Planta Medica · 2002 · 22 citations