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The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Finasteride effectively treats male hair loss, improving growth and density.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Dicentrine reduced heart disease risk factors in rats, T-588 protected mice brains without side effects, Provir blocked herpes virus and lessened mouse symptoms, and LY191704 could treat hair loss and prostate issues.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Annurca apple extract improved hair growth in mice and could potentially prevent hair loss.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.