30 citations
,
May 2016 in “Expert Opinion on Biological Therapy” New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
2 citations
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November 2015 in “Journal of Investigative Dermatology” RANKL improves the immune response against herpes simplex virus by enhancing T cell activation and could help develop better treatments or vaccines.
January 2024 in “Biomedicines” The review shows that skin symptoms like chronic fungal infections, hair loss, and skin depigmentation are key for early detection and management of APECED.
52 citations
,
March 2010 in “British Journal of Dermatology” Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
31 citations
,
May 2021 in “Journal of endocrinological investigation” APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
22 citations
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November 2011 in “Journal of Supercritical Fluids” Rice bran extract might help prevent hair loss.
2 citations
,
May 2021 in “Case reports in dermatological medicine” A 28-year-old man with type 1 diabetes had skin and hair issues due to zinc deficiency.
12 citations
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February 2023 in “Journal of Personalized Medicine” Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Blood pressure drugs can cause skin lupus, but it improves after stopping the drug. The glycoprotein D vaccine works against genital herpes in some women, and the HPV-16 vaccine reduces HPV-16 infection and related diseases. More frequent light therapy clears psoriasis faster. A cream called imiquimod effectively treats a type of skin cancer. Iron supplements don't necessarily help with chronic hair loss in women.
13 citations
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October 2016 in “Medical Hypotheses” Hair characteristics might be early signs of Type 2 Diabetes and could help with early prevention.
2 citations
,
December 2023 in “Journal of clinical immunology” Ruxolitinib significantly improves multiple autoimmune conditions in APS-1 patients.
9 citations
,
January 2007 in “Gynecological Endocrinology” A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.
21 citations
,
July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.
January 2003 in “Springer eBooks” Certain genes are linked to type 1 and type 2 diabetes in kids, and changes in these genes can also cause other diabetes-related conditions.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Blood pressure drugs can cause skin lupus, early treatment is key for baby herpes and diabetic foot ulcers, a certain vaccine works against genital herpes and HPV in women, more frequent light therapy helps psoriasis, smoking and drinking can worsen psoriasis, a cream clears up a type of skin cancer, and low iron levels don't cause chronic hair loss.
4 citations
,
September 2023 in “Stem cell research & therapy” Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
3 citations
,
May 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ILC1 cells contribute to hair loss in alopecia areata.
September 2023 Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.
July 2003 in “Journal of Cutaneous Medicine and Surgery” High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Certain drugs can cause lupus, stopping these drugs is the main treatment. NB-UVB phototherapy clears psoriasis faster when applied three times a week. Monoclonal antibodies and oral pimecrolimus are effective in treating psoriasis. Smoking and drinking are linked to psoriasis in men. No direct link between low iron and hair loss was found. Vaccines are effective against genital herpes and human papillomavirus type 16.
4 citations
,
November 2022 in “Acta dermato-venereologica” People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.
225 citations
,
April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
185 citations
,
December 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
141 citations
,
August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
January 2017 in “Postepy Dermatologii I Alergologii” The CRH/CRH-R1 system might be involved in causing lichen planus.
May 2016 in “Journal of Investigative Dermatology” Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
14 citations
,
August 2018 in “Frontiers in Cellular and Infection Microbiology” Dengue virus can infect human hair follicle cells and may cause hair loss.
11 citations
,
May 2021 in “Journal of Medical Virology” Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.
140 citations
,
January 2018 in “Journal of Controlled Release” Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.
1 citations
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August 2022 in “Biomedicines” Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.