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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Testosterone's muscle-building effects do not require its conversion to DHT.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Rats had lasting erectile problems after stopping a certain medication.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Dutasteride may help shrink prostate cancer tumors.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Suppressing certain hormones might help prevent prostate cancer.

Androgens can both increase body hair and cause scalp hair loss.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.