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Four-amino acid part makes enzyme sensitive to finasteride.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Compound 15a was effective in inhibiting 5α-reductase.

Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.

Ageratum conyzoides L. extract may effectively and safely treat hair loss.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

Certain drugs, especially antiandrogens and spironolactone, significantly increase the risk of gynecomastia.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Rats had lasting erectile problems after stopping a certain medication.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.