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Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Hair loss drugs may cause sexual issues and infertility in men.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Solanum nigrum may help treat hair loss.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Testosterone's muscle-building effects do not require its conversion to DHT.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Grateloupia elliptica extract may help prevent hair loss and promote hair growth.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Finasteride improves hair growth in men with androgenetic alopecia.

Teak leaf extract contains compounds that could help treat hair loss.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Finasteride safely lowers DHT levels without affecting testosterone.