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The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

The study concluded that severity of Frontal fibrosing alopecia is not linked to how long someone has it, can start before menopause, and eyebrow loss may be an early sign.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

5-alpha-reductase inhibitors help treat urinary symptoms from an enlarged prostate.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.

Four-amino acid part makes enzyme sensitive to finasteride.

Frontal fibrosing alopecia is a challenging hair loss condition with no known cause or definitive treatment.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

Some treatments can stabilize Frontal Fibrosing Alopecia, but more research is needed to find effective treatments, and hair transplants often fail.

Older patients sticking to their prostate medication saw lasting health benefits.

Dutasteride caused more penile tissue changes than finasteride, possibly increasing erectile dysfunction risk.

Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.

Dutasteride is the most effective hair loss treatment after 24 weeks, but finasteride leads to the most hair growth after 48 weeks.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Dermatologists recommend oral dutasteride for male hair loss, low-dose oral minoxidil for female hair loss, and a multidisciplinary approach for young patients, with caution during pregnancy.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.

Men can experience female pattern hair loss, needing different treatments.

Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.

The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.