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Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Certain genes are linked to the quality of cashmere in goats.

Epimedium extract helps increase skin pigmentation and could be a new treatment for conditions with reduced pigmentation.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.

Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

A hair transplant using hair from the back of the head and pubic area was successful in creating a feminine hairline for a male-to-female transgender person.

As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

Hair samples can be used to create stem cells easily and non-invasively.

Polycystic ovary syndrome and iron overload share similar symptoms and can be potentially treated with blood removal, diet changes, and probiotics.

Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.

Hair in mammals likely evolved from glandular structures, not scales.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Three finasteride forms exist; "form X" doesn't.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Follicular Unit Extraction (FUE) hair transplant is less invasive, leaves no scars, and has quicker recovery times, but it's more time-consuming and challenging. Automation helps speed up the process and improve graft survival, reducing the need for traditional strip surgery.

Tectoridin helps human hair cells grow and makes mouse hair longer, suggesting it could treat hair loss.

Lipin-1 is important for skin cell differentiation and skin barrier function.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Various techniques and tools for hair restoration were presented in 1998, including a mathematical model for donor area, use of lasers in surgery, methods for controlling grafted hair direction, and ways to increase graft yield. Satisfaction rates were around 39%, and studies showed trauma and dehydration can damage hair follicles.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Niosomes are a promising and effective way to deliver drugs through the skin.