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Oestrogens are key for bone growth during puberty in both boys and girls.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Stem cell self-renewal is complex and needs more research for full understanding.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Too much androgen can cause hair loss; finasteride may help.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Oxidative stress contributes to hair graying and loss as we age.

Finasteride effectively treats baldness but may cause sexual side effects.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.