277 citations,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
146 citations,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.
3 citations,
September 2005 in “Experimental dermatology” The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
6 citations,
January 2015 in “Evidence-based Complementary and Alternative Medicine” Saw palmetto extract may help treat brain tumors by blocking a specific growth signal and blood vessel formation.
64 citations,
March 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” GPRC5D is linked to the formation of hair, nails, and certain tongue areas.
13 citations,
April 2010 in “Journal of dermatological science” Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.
5 citations,
January 2021 in “Frontiers in Cell and Developmental Biology” Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.
January 2022 in “International Journal of Medical Sciences” Cedrol may be an effective treatment for colorectal cancer.
61 citations,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
42 citations,
July 2012 in “PLOS ONE” Estrogen can temporarily slow down hair growth but this can be reversed.
7 citations,
January 2023 in “Frontiers in Cell and Developmental Biology” Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
2 citations,
August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
130 citations,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
6 citations,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
37 citations,
January 2011 in “Annals of Dermatology” ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.
5 citations,
June 2019 in “British Journal of Dermatology” Tofacitinib was more effective than apremilast in treating hair loss in a mouse model of alopecia areata.
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
71 citations,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
39 citations,
August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
15 citations,
September 2008 in “Archives of Dermatological Research” Roxithromycin, an antibiotic, can increase hair growth and might be used as a treatment for hair loss.
208 citations,
January 2013 in “Lab on a Chip” The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.
104 citations,
January 2016 in “Food & Function” Olive oil compounds may help prevent cancer in animals, but human results are mixed.
96 citations,
October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
81 citations,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
72 citations,
October 2009 in “The FASEB journal” TRH stimulates human hair growth and extends the hair growth phase.
67 citations,
August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
64 citations,
January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
32 citations,
January 2007 in “Biological & Pharmaceutical Bulletin” Minoxidil and retinol together help hair grow.
30 citations,
September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
26 citations,
October 2007 in “Experimental Dermatology” L-Carnitine-L-tartrate may help hair grow and prevent hair loss.