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This study suggests that Bim and Puma proteins play a role in hair follicle development and maintenance, although they only partially overlap with apoptosis during normal hair cycle stages.

This case report describes a 35-year-old male with Type 2 diabetes who experienced scalp hair loss after increasing his dose of Teneligliptin without supervision, which resolved after discontinuing the medication.

Reduced AhR signaling in HS tunnels leads to persistent inflammation and microbial imbalance.

This study found that hairline lowering surgery using a bone tunneling technique without Endotine effectively reduced forehead length and achieved high patient satisfaction among 91 participants, with results sustained over 12 months and minimal reported complications.

This study constructed a consensus single-cell atlas for hidradenitis suppurativa tunnels, identifying distinct fibro-inflammatory microenvironments with potential drug targets, suggesting TNF blockade alone may not be effective for all lesion types.

This study's new single-cell atlas of hidradenitis suppurativa tunnels identifies distinct fibro-inflammatory microenvironments, suggesting that TNF blockade may not address the primary pathway in many lesions.

This study created a comprehensive single-cell atlas of hidradenitis suppurativa tunnels, identifying distinct microenvironmental endotypes linked to specific signaling pathways, suggesting that TNF blockade may not effectively address predominant pathways in many lesions and highlighting the potential for individualized treatment strategies.

This study constructed a consensus single-cell atlas of hidradenitis suppurativa tunnels, identifying distinct microenvironmental endotypes with different inflammatory and fibrotic profiles, suggesting that TNF blockade may not be sufficient for addressing all lesions.

This abstract describes a clinical trial registered in the Chinese Clinical Trial Registry, with its first participant enrolled on September 30, 2024; no specific study outcomes are reported.

This case report describes a 62-year-old woman diagnosed with undifferentiated connective tissue disease and renal amyloidosis, presenting symptoms like joint pain, Raynaud's phenomenon, and carpal tunnel syndrome.

This review reports that the unique tunnel structures in advanced hidradenitis suppurativa impair quality of life and resist biological therapy, with their formation involving complex cellular and molecular interactions, including microbial dysbiosis, all contributing to ongoing inflammation and scarring.

This study found that Polycomb repressive complex 1 is crucial for skin development and stem cell specification, influencing gene activity beyond its known repressor functions.

This study suggests that silver-coating may enhance the healing of exit sites in peritoneal catheters in rats, with similar tunnel histomorphology indicating favorable biocompatibility compared to standard catheters.

This study reported successful outcomes in over 40 patients undergoing reparative surgical techniques for previously unsuccessful hair restoration, with significant improvements in appearance despite potential challenges like limited donor hair and scalp scarring.

This study designed a micromold template for creating controlled-sized, multicellular tumor spheroids, finding that HEK-293 cells formed consistent spheroids with high circularity and viability after 7 days, influenced by cell seeding density and treatment conditions.

This study identified a new FAK isoform, FAKΔe4, which is regulated by ECM stiffness and affects cell migration, invasion, and mechanosensing in human-derived data and engineered models.

This study found that dietary serine levels influence hair follicle stem cells' ability to balance hair regeneration and wound repair, offering insights for potential interventions to accelerate wound healing.

This review summarized COVID-19's symptoms, transmission, and long-term effects, highlighting that vaccines effectively mitigate prolonged symptoms and suggesting multidisciplinary rehabilitation for post-COVID conditions.

This article discusses how mechanical stress may contribute to the development of hidradenitis suppurativa lesions, drawing on historical research and highlighting the possible role of IL-17-mediated inflammation.

This study found that local platelet-rich plasma injection improved mid-term outcomes for carpal tunnel syndrome more effectively than other conservative treatments, although long-term effects and standardization need further research.

This study outlines a planned double-blind, randomized controlled trial to assess the efficacy of two different doses of PRP injections for moderate carpal tunnel syndrome, focusing on variations in symptom severity, ultrasound parameters, and nerve electrophysiology, though results are not yet reported.

This review discusses the measurement of patient satisfaction in acne scar treatment studies, highlighting the need for standardized satisfaction questions to enhance comparability and future research; it reports no new clinical results.

This study introduced and validated a reliable and reproducible metal-free mouse model for ACLR surgery, providing a new tool to investigate the molecular mechanisms of graft-tunnel healing.

This study found that 70-MHz ultrasound can detect early signs of hidradenitis suppurativa linked to severity, including hair follicle abnormalities and keratin fragmentation, aiding in diagnosis and management.

The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.

This study introduced a new classification system for distinguishing between anagen VI and early catagen stages in human hair follicle organ culture, using it to confirm eflornithine's ability to induce premature catagen.

This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.

This study demonstrates that YAP and TAZ are essential for initiating basal and squamous cell carcinomas in mice, and suggests targeting these pathways could be beneficial for treating skin cancers.