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In this study, activating TRPV1 nociceptors in mice skin stimulated dormant hair follicles and promoted hair growth through a mechanism involving dermal macrophages, fibroblasts, and neuropeptides, highlighting a new role for nociceptors in tissue recovery after injury.

This study found that S. scabiei infestation in rabbits leads to epidermal thickening possibly due to apoptosis-related proliferation and keratinization of the skin.

In this study, researchers found that psoriasis patients with untreated lesions showed increased activation of defensins, matrix metalloproteinases, and neuropeptides, which may be stimulated by specific inflammation pathways.

In this study, Dguok deficiency in mice led to premature hair greying due to a loss of melanocyte stem cells and mature melanocytes, with increased oxidative stress and cell death; treatment with an antioxidant mitigated these effects, suggesting DGUOK's importance in hair pigmentation maintenance.

In this study, researchers found that the histone demethylase UTX is crucial for regulating skin differentiation through retinoic acid signaling, mainly impacting females, as males compensate with a Y-linked paralog.

In this study, researchers observed that applying negative pressure to nude mice led to a significant increase in hair follicle growth and angiogenesis, suggesting potential for hair regeneration through mechanisms involving SOX-9, LHX-2, and β-catenin mediation.

This study found that adipose-derived stem cells with DKK1 knocked out using CRISPR/Cas9 promoted hair growth in an alopecia areata model more effectively than untreated stem cells, suggesting DKK1 is a potential therapeutic target for this condition.

The research found that while Dnmt3a and Dnmt3b are not necessary for skin homeostasis in mice, the loss of Dnmt3a increases squamous tumor formation from carcinogens, and combined deletion of both results in more aggressive and metastatic tumors.

This study observed that after hair cell loss in the mouse cochlea, supporting cells were replaced by migrating non-specialised cells, with genetic background affecting the rate of tissue re-organization.

This research suggests that defects in keratinocyte differentiation due to putrescine accumulation in SSAT transgenic mice lead to skin changes and hair loss, and reducing putrescine can promote hair regrowth.

This study found that EP 2 signaling is crucial for macrophage recruitment and inflammatory regulation in the injured heart, impacting cardiac repair processes.

In this study, shear-thinning silk nanofiber hydrogels were found to enhance retention of mesenchymal stem cells and accelerate wound healing in rat models.

This laboratory study found that collagen matrices with high-sulfated hyaluronan may enhance the cultivation of human keratinocytes and melanocytes from hair follicles for epidermal graft development.

A feedback loop between LRH and RSL4 controls root hair growth in Arabidopsis.

This study observed that GREM2 was specifically and robustly expressed in the dermal sheath cup of hair follicles during various hair cycle phases, suggesting its significant role in regulating hair cycling processes through BMP signaling.

This study found that overexpressing the CLE peptide SlCLE10 in tomatoes increased root hair length and improved drought tolerance, suggesting its potential for enhancing crop resilience to osmotic stress.

This study found that regulatory T cells accumulate in hair follicle epithelium via the Cxcr4-Cxcl12 axis, partially influenced by glucocorticoid receptor signaling, promoting hair regeneration; similar mechanisms were observed in human and murine skin.

This review highlights the potential roles of long non-coding RNAs (lncRNAs) in malignant brain tumors, reporting that further research into their involvement in therapy resistance and cancer pathways could improve diagnosis and treatment outcomes.

This review compiles current research on the role of long non-coding RNAs in regulating muscle growth and regeneration processes, particularly their influence on Duchenne muscular dystrophy, and reports no new clinical results.

This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.

Low-frequency electromagnetic fields may help treat hair loss by promoting hair regrowth.

In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.

This study found that Morus alba root extract activates β-catenin in hair follicle dermal papilla cells, promoting the transition to the anagen phase and enhancing hair growth factor secretion.

This study found that Tideglusib enhances wound healing in aged rats by activating the PI3K/Akt pathway, suggesting its potential for medical and cosmetic applications targeting age-related skin changes.

In this study, low-dose BPA was associated with induced prostatic hyperplasia in rats, potentially mediated by COX-2 and L-PGDS through pathways involving cell proliferation and apoptosis.

This review provides a comprehensive overview of apoptosis-related molecules in head development, highlighting caspases' roles and associated abnormalities in tissues like the brain, sensory organs, skin, and bones, without reporting new results.

This review examines the anti-alopecia effects of plant-derived phytochemicals and their mechanisms for promoting hair growth, but it reports no new clinical findings.

This study found that the combination of epidermal growth factor and Jagged1 significantly stimulated hair growth in mice with androgen-suppressed conditions, suggesting potential therapeutic implications for androgenetic alopecia.

This study identified neuropilin-1 as the receptor for FOL-026 and showed that it stimulates angiogenesis and cell growth, suggesting potential for vascular repair and enhanced angiogenesis therapies.

In this study, miR-221 was identified as a key factor in androgenetic alopecia pathogenesis due to its role in suppressing hair growth by interacting with androgen receptors and affecting related pathways.