research Micro-RNA-31 Controls Hair Cycle-Associated Changes in Gene Expression Programs of the Skin and Hair Follicle
miR-31 regulates hair growth by controlling gene expression in hair follicles.
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780-810 / 1000+ resultsresearch The Molecular Revolution in Cutaneous Biology: Noncoding RNAs as New Molecular Players in Dermatology and Cutaneous Biology
Non-coding RNAs are crucial for skin development and health.
research MAIT Cells in COVID-19: Heroes, Villains, or Both?
MAIT cells may help fight COVID-19 but also contribute to severe inflammation.
research Proteomics as a Tool to Improve Novel Insights into Skin Diseases: What We Know and Where We Should Be Going
Proteomics combined with other technologies can lead to a better understanding of skin diseases.
research Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease
Zebrafish are useful for studying and developing treatments for human skin diseases.
research Molecular Mechanisms of Y Chromosome Loss and UTY Gene Activity
Loss of the Y chromosome and UTY gene activity increases cancer risk in men.
research Male Pattern Baldness and Risk of Incident Skin Cancer in a Cohort of Men
Male pattern baldness is linked to a higher risk of certain skin cancers, especially on the scalp.
research Role of Beta-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Essential Role of STAT3 Signaling in Hair Follicle Homeostasis
STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
research Signaling Pathways in Hair Aging
Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The treatment was ineffective in humans.
research Cyclin-Dependent Kinase 4 Expression Alters the Number of Keratinocyte Stem Cells in the Mouse Hair Follicle
Changing CDK4 levels affects the number of stem cells in mouse hair follicles.
research Red Ginseng (Panax Ginseng Meyer) Oil: A Comprehensive Review of Extraction Technologies, Chemical Composition, Health Benefits, Molecular Mechanisms, and Safety
Red ginseng oil is believed to have various health benefits and is safe, but more research is needed to fully understand how it works.
research BMI1 Is Required for Melanocyte Stem Cell Maintenance and Hair Pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research The Rational Role Of Polyamines In Epidermal Differentiation
Adjusting polyamine levels could help treat skin disorders like psoriasis and skin cancer.
research Is Dehydroepiandrosterone a Hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Common Pathologic Pathways: A Single Prescription Dream?
The conclusion suggests that treatments targeting root causes of chronic diseases may be developed by focusing on gene expression and lifestyle factors.
research Short-Term Biomarkers of Cigarette Smoke Condensate Tumor Promoting Potential in Mouse Skin
Cigarette smoke condensates increase tumor-promoting markers in mouse skin, especially around hair follicles.
research Non-Invasive Diagnosis of Prostate Cancer from Body Fluids Using a Panel of Tumor Suppressor Genes
Blood tests for tumor cells could improve prostate cancer diagnosis and treatment; hair loss severity linked to a gene affecting prostate conditions.
research Anti-Cancer Properties of Olive Oil Secoiridoid Phenols: A Systematic Review of In Vivo Studies
Olive oil compounds may help prevent cancer in animals, but human results are mixed.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis
Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
research News in Brief
Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.
research Activity of Sorafenib Against Desmoid Tumor/Deep Fibromatosis
Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.
research Potential of Nano-Phytochemicals in Cervical Cancer Therapy
Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.
research BRCA2 in Abscission: Role in Cytokinesis and Recruitment of Abscission Regulators
The tumor suppressor BRCA2 helps in cell division by bringing key proteins to the area where cells split.
research Annotated Patent Selections
The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
research Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor-β1/β2, and p63 in Sebaceous and Follicular Tumors
The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.