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    1. Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin. PubMed · 1997 · 233 citations
    2. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations
    3. Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment GenomeBiology.com · 2015 · 153 citations
    4. Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice Oncogene · 1997 · 147 citations
    5. CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice Cancer Research · 2007 · 141 citations
    6. Overexpression of protein kinase C-α in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2 and TNF-α expression but not tumor promotion Journal of Cell Science · 1999 · 135 citations
    7. Genetic architecture of mouse skin inflammation and tumour susceptibility Nature · 2009 · 133 citations
    8. Tumor Angiogenesis and Anti-angiogenic Therapy The Keio Journal of Medicine · 2012 · 123 citations
    9. Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion. PubMed · 2000 · 99 citations
    10. Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN Journal of the National Cancer Institute · 2012 · 81 citations
    11. Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice. PubMed · 2003 · 79 citations
    12. Induction of dark keratinocytes by 12-O-tetradecanoyl-phorbol-13-acetate and mezerein as an indicator of tumor-promoting efficiency Carcinogenesis · 1980 · 77 citations
    13. Hair Follicle–Derived Blood Vessels Vascularize Tumors in Skin and Are Inhibited by Doxorubicin Cancer Research · 2005 · 76 citations
    14. Tumour regression predicts higher risk of sentinel node involvement in thin cutaneous melanomas British Journal of Dermatology · 2003 · 68 citations
    15. Stem cell quiescence acts as a tumour suppressor in squamous tumours Nature Cell Biology · 2013 · 66 citations
    16. Divergent roles of HDAC1 and HDAC2 in the regulation of epidermal development and tumorigenesis The EMBO Journal · 2013 · 65 citations
    17. Spontaneous Squamous Cell Carcinoma Induced by the Somatic Inactivation of <i>Retinoblastoma</i> and <i>Trp53</i> Tumor Suppressors Cancer Research · 2008 · 64 citations
    18. Alopecia areata as another immune‐mediated disease developed in patients treated with tumour necrosis factor‐α blocker agents Journal of the European Academy of Dermatology and Venereology · 2010 · 61 citations
    19. Silk‐Inspired In Situ Hydrogel with Anti‐Tumor Immunity Enhanced Photodynamic Therapy for Melanoma and Infected Wound Healing Advanced Functional Materials · 2021 · 59 citations
    20. Cylindroma as Tumor of Hair Follicle Origin Journal of Investigative Dermatology · 2006 · 57 citations
    21. The Vitamin D Receptor as Tumor Suppressor in Skin Advances in experimental medicine and biology · 2020 · 55 citations
    22. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    23. Cellular plasticity in reprogramming, rejuvenation and tumorigenesis: a pioneer TF perspective Trends in Cell Biology · 2023 · 45 citations
    24. Homeostasis, regeneration and tumour formation in the mammalian epidermis The International Journal of Developmental Biology · 2018 · 44 citations
    25. Roles of tumor suppressors in regulating tumor-associated inflammation Cell Death & Differentiation · 2014 · 44 citations
    26. Tumor Mapping in 2 Large Multigenerational Families With CYLD Mutations Archives of Dermatology · 2009 · 44 citations
    27. Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine Disease Models & Mechanisms · 2018 · 40 citations
    28. Tumor suppressor activity of ODC antizyme in MEK-driven skin tumorigenesis Carcinogenesis · 2006 · 37 citations
    29. Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis PloS one · 2014 · 29 citations
    30. Tumor Necrosis Factor-Alpha and Polycystic Ovarian Syndrome: A Clinical, Biochemical, and Molecular Genetic Study Genetic Testing and Molecular Biomarkers · 2014 · 26 citations