research HIF-2α/ARNT Complex Regulates Hair Development via Induction of p21 Waf1/Cip1 and p27 Kip1
The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.
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research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Emerging Roles of Transit-Amplifying Cells in Tissue Regeneration and Cancer
Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
research Applications of Exosomal miRNAs from Mesenchymal Stem Cells as Skin Boosters
Exosomal miRNAs from stem cells can help improve skin health and delay aging.
research Epithelial Cells in the Hair Follicle Bulge Do Not Contribute to Epidermal Regeneration After Glucocorticoid-Induced Cutaneous Atrophy
Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Cancer Risk in Polycystic Ovary Syndrome Patients: Common Treatments and Future Perspectives
PCOS may increase the risk of certain cancers.
research Does Prostaglandin D2 Hold the Cure to Male Pattern Baldness?
Prostaglandin D₂ might be targeted for new male pattern baldness treatments.
research DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells
Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
research Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration
Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
research HIF1A Stabilization in the Human Hair Follicle Promotes Glycolysis
Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
research Flexible Fate Determination Ensures Robust Differentiation in the Skin Hair Follicle
Hair follicle stem cells can change their role to ensure proper hair development.
research FLCN Regulates Transferrin Receptor 1 Transport and Iron Homeostasis
FLCN helps control iron levels in cells.
research Bendamustine: An Old Drug in the New Era for Patients with Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia
Bendamustine, often combined with other drugs, is effective and less toxic for certain blood cancers, but less effective for young, fit patients with CLL.
research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Epidermal Differentiation Complex: A Review on Its Epigenetic Regulation and Potential Drug Targets
Understanding how EDC genes are regulated can help develop better drugs for skin diseases.
research Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition
Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
research A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention
Grape seed extract may safely and effectively help prevent lung cancer.
research Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study
Botox increased hair count in men with baldness and might work by improving scalp blood flow.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter
Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
research Dietary Vitamin A Impacts Refractory Telogen
Eating too much or too little vitamin A can cause hair loss.
research A Novel Connexin 26 Mutation in a Patient Diagnosed with Keratitis–Ichthyosis–Deafness Syndrome
A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.
research Normal Stem Cells and Cancer Stem Cells: Similar and Different
Deregulation of stem cell function is central to the development of some cancers.
research An Overview of Anti-Inflammatory, Antioxidant, Anti-Cancer, Anti-Hyperlipidemic, Neuroprotective and Muscle Relaxant Effects of Natural Flavonoid, Apigenin; A Review
Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.
research Cutaneous Lupus Erythematosus: A Review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology
Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
research Control by a Hair’s Breadth: The Role of MicroRNAs in the Skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.