research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.
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90-120 / 1000+ resultsresearch Cell Polarization Defects in Early Heart Development
Defects in certain proteins cause major heart abnormalities during early development.
research Enzymes
Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.
research Anthocyanin as Colorectal Anticancer: A Brief Review
Anthocyanins from fruits and vegetables may help prevent and treat colorectal cancer safely.
research Chemistry, Pharmacology, and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein
Disulfide bonds make keratin in hair stronger and tougher.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research Minoxidil Regulates Aging-Like Phenotypes in Rat Cortical Astrocytes In Vitro
Minoxidil may help reduce aging effects in brain cells.
research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Exosomal MicroRNA-Based Therapies for Skin Diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
research Antisense Oligonucleotide Targeting Fibroblast Growth Factor Receptor-1 Stimulates Cellular Activity of Hair Follicles in an In Vitro Organ Culture System
Targeting FGFR-1 with antisense oligonucleotides may help treat baldness by increasing hair follicle activity.
research Analysis of the MicroRNA Expression Profile of Normal Human Dermal Papilla Cells Treated with 5α-Dihydrotestosterone
DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
research Parathyroid Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin
PTHrP and its receptor can control blood vessel growth and hair development in mouse skin.
research Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions Toward Clinical Reality
A new model using mice with human hair follicles helps better understand hair loss from chemotherapy.
research Understanding the Role of Glycogen Metabolism in Human Hair Follicle Biology
Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
research Vitamin A Regulates Dermal Papilla Cell Proliferation and Apoptosis Under Heat Stress via IGF1 and Wnt10b Signaling
Vitamin A helps rabbit skin cells grow and survive heat stress.
research Hot Topics in Pediatric Dermatology
Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.
research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research The Force Is Strong with This One: Metabolism Overpowers Stem Cell Fate
Metabolism plays a key role in determining stem cell fate.
research Testosterone Therapy in Women: Myths and Misconceptions
Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
research The Non-Neuronal and Nonmuscular Effects of Botulinum Toxin: An Opportunity for a Deadly Molecule to Treat Disease in the Skin and Beyond
Botulinum toxin has potential for treating various skin conditions and improving wound healing.
research Protection Against Chemotherapy-Induced Alopecia
No treatment fully prevents hair loss from chemotherapy yet.
research Green Tea in Dermatology: Myths and Facts
Green tea may help with skin health and protect against UV damage, but more research is needed to confirm its safety and effectiveness.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Main Plenary Sessions: Summaries of Papers
The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.
research Oral Contraceptive Pill Treatment Alters Gene Expression of Inflammatory Markers in Polycystic Ovary Syndrome Women
Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
research Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
research An In Situ Chemotherapy Drug Combined with Immune Checkpoint Inhibitor for Chemoimmunotherapy
Combining specific nanoparticles with immune therapy significantly improves cancer treatment.
research Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells
Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.