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Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

A man with KID syndrome developed a rare cancer in a long-term skin infection.

Epidermal stem cells show promise for future dermatology treatments due to ongoing advancements.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Photodynamic therapy is the preferred treatment for skin precancer due to its effectiveness and safety.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Valentina Greco's research shows that the environment around hair follicle stem cells is more crucial for regeneration than the stem cells themselves.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.