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Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.

Targeting the Smoothened receptor shows promise for treating certain cancers.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

Our microbiome may affect the development of the hair loss condition Alopecia Areata, but more research is needed to understand this relationship.

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

Psoriasis involves immune and genetic factors, and understanding these can improve treatments.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Targeting TGFβ can improve skin immunity in older people.

Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.

Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.

Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

TLR4 is important in aging-related diseases and could be a new treatment target.

Four specific genes are linked to keloid formation and could be potential treatment targets.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

Metformin might help treat certain skin conditions, but more research is needed.

Finasteride in male rats causes liver and metabolic issues in their offspring.