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EDA signaling is linked to skin disorders, various cancers, and liver disease.

Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.

Increasing EGR1 levels makes hair root cells grow faster.

The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.

High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.

Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Notch signaling is essential for healthy skin and hair follicle maintenance.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

Testosterone may slow down wound healing and increase inflammation.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Older skin has higher cancer risk due to inflammation and stem cell issues.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Chrysin makes docetaxel more effective and reduces its side effects in lung cancer treatment.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.