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PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Skin symptoms can indicate endocrine disorders and have various treatments.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Type-2 immunity may influence skin diseases and could be targeted for treatment.

SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

Reproductive hormones play a crucial role in breast cancer development and treatment challenges.

Leontopodium alpinum extract may help reduce hair shedding by keeping hair in the growth phase longer.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.

The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

PCOS affects a similar percentage of Black and White women in the Southeastern United States.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

PCOS affects about 4% of women in the southeastern U.S. equally across Black and White populations.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.