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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.

Female hair loss is often hereditary and can be treated with medication, hair transplants, and lasers.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.

Cardiovascular drugs can cause various skin problems, so recognizing these reactions is important.

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

Low-dose UVB light improves hair growth effects of certain stem cells by increasing reactive oxygen species.