48 citations,
January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Chemokine signaling is important for hair development.
January 2019 in “Springer eBooks” Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
105 citations,
September 1995 in “Journal of The American Academy of Dermatology” Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
66 citations,
February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
30 citations,
January 2013 in “Obesity Surgery” Bariatric surgery affects skin health, causing both direct complications and changes in existing skin conditions, often related to nutritional deficiencies.
7 citations,
March 2022 in “International Journal of Molecular Sciences” FGF21 can help reduce skin inflammation caused by C. acnes.
4 citations,
August 2007 in “Journal of The American Academy of Dermatology” The document discusses a condition causing hair loss after surgery and a type of rosacea affecting the nose, with treatments including surgery and laser therapy.
3 citations,
May 2018 in “European Journal of Dermatology” Photodynamic therapy may not work for erythroplasia of Queyrat and could lead to invasive squamous cell carcinoma.
1 citations,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
83 citations,
June 2018 in “Frontiers in immunology” Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
66 citations,
January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
60 citations,
May 2015 in “Archives of dermatological research” PPAR agonists show promise for skin conditions but need more research before being a main treatment.
13 citations,
March 2014 in “Journal of Clinical Laboratory Analysis” Higher MIF levels in alopecia areata patients suggest it could be a treatment target and disease predictor.
9 citations,
July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
6 citations,
May 2020 in “Scientific reports” Researchers identified genes and proteins that may influence wool thickness in sheep.
January 2018 in “Springer eBooks” Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.
Female hair loss is often hereditary and can be treated with medication, hair transplants, and lasers.
200 citations,
October 2009 in “European journal of endocrinology” Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
192 citations,
January 2015 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause serious skin problems that need careful management.
178 citations,
August 2016 in “Advances in wound care” New effective scar treatments are urgently needed due to the current options' limited success.
176 citations,
January 2003 in “Journal of Investigative Dermatology” Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.
174 citations,
April 2005 in “The American journal of pathology (Print)” Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.
159 citations,
December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
127 citations,
December 2005 in “Experimental Dermatology” Stress can stop hair growth in mice, and treatments can reverse this effect.
65 citations,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
54 citations,
September 2012 in “Dermatologic Clinics” Some medications can cause hair loss, but stopping the drug usually leads to recovery within 3 months.
46 citations,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
44 citations,
January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
39 citations,
January 2016 in “PubMed” Understanding how EDC genes are regulated can help develop better drugs for skin diseases.