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Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Aged individuals heal wounds less effectively due to specific immune cell issues.

Women with PCOS are much more likely to have sleep problems and should be checked for them.

Stopping certain drugs can improve skin conditions, arsenicosis affects over half of a Bangladeshi village, males are more vulnerable, and certain treatments are effective for warts, acne, and psoriasis. Smoking and drinking are linked to psoriasis in men, a cream helps with a type of skin cancer, and low iron levels don't directly cause chronic hair loss in women.

FGF21 can help reduce skin inflammation caused by C. acnes.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Type I interferons play a key role in the development of various skin diseases.

IL-36α helps grow new hair follicles and speeds up wound healing.

IL-1α levels are higher in alopecia areata patients, suggesting a role in the disease.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.

Inflammation around hair follicles leads to hair loss, and treatments should focus on reducing this inflammation and other factors for effectiveness.

Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.

COVID-19 can cause temporary hair loss, which is commonly reversible with treatment.

Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.

Borneol Essential Oil could be a natural and safe acne treatment.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

Infliximab can trigger lupus-like symptoms in Crohn's disease patients.

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

RANKL causes lymph nodes to grow by making certain cells multiply.

Phyllotex™ extract was found to significantly promote hair growth and protect against hair loss.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.