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A group has developed therapies that show promise for treating cancer and various other conditions.

High TSPEAR levels in colorectal cancer predict worse outcomes.

Certain flavonoids can improve the growth of pigmented hair in mice.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Stem cell niches support, regulate, and coordinate stem cell functions.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Skin fat helps with body temperature control and has other active roles in health.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.