research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
Search
for
Sort by
Research
600-630 / 1000+ results 
research Unlocking the Medicinal Potential of Plant-Derived Extracellular Vesicles: Current Progress and Future Perspectives
Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.
research Actinic Keratosis: Risk Factors, Clinical Diagnosis, and Therapeutic Aspects. Part I
Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires various treatments to prevent this.
research Actinic Keratosis: Risk Factors, Clinical Diagnosis, and Therapeutic Aspects. Part I
Actinic keratosis is a sun-induced skin condition that can potentially turn into skin cancer and requires treatment to prevent malignancy.
research Exosomes: Breakthrough in Regenerative Medicine and a Way to Improve Quality of Life
Exosomes can help repair and heal tissues, improving health and vitality.
research Robotic Hair Transplantation – Artificial Intelligence Plus Human Touch
Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.
research Biomedical Engineering Approaches for the Delivery of JAGGED1 as a Potential Tissue Regenerative Therapy
JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.
research Drug Delivery Systems Based on Microneedles for Dermatological Diseases and Aesthetic Enhancement
Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
research Investigations on Kaempferol, Quercetin, and Other Flavonoids in Aquatic Plants of Iraqi Marshlands
Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.
research Novel Mechanism of UVB-Mediated Pigmentation Through the Axis of ATP-P2X7
Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.
research Prostaglandin Related Distinct Regenerative Activities in Hair Follicles Following Radiation Injury
HPV infection is linked to better survival in advanced anal cancer, higher radiation doses improve survival, especially in HPV-negative patients, and prostaglandin E₂ pretreatment can protect mouse hair follicles from radiation damage.
research ILDS Newsletter No. 29: Efforts to Improve Lives of Patients with Albinism in Sub-Saharan Africa
The ILDS Newsletter reported on efforts to support albinism patients in Tanzania and dermatological conferences.
research WWOX Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin
WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
research BMI1 Is Required for Melanocyte Stem Cell Maintenance and Hair Pigmentation
BMI1 is essential for preventing hair greying and maintaining hair color.
research Prolactin and Hyperprolactinemia in Female Reproductive Endocrinology – An Update
Too much prolactin can cause menstrual problems, infertility, and sexual issues in women.
research The Evolutionary Impact of Androgen Levels on Prostate Cancer in a Multi-Scale Mathematical Model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Notch Signaling Is Significantly Suppressed in Basal Cell Carcinomas and Activation Induces Basal Cell Carcinoma Cell Apoptosis
Activating Notch signaling can kill basal cell carcinoma cells.
research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Epigenetics of Colorectal Cancer
Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.
research Pulmonary Manifestations of Birt-Hogg-Dubé Syndrome
People with Birt-Hogg-Dubé syndrome often have lung problems and delayed diagnosis, and better recognition of CT scan signs could improve diagnosis and management.
research Targeted Overexpression of the Angiogenesis Inhibitor Thrombospondin-1 in the Epidermis of Transgenic Mice Prevents Ultraviolet-B-Induced Angiogenesis and Cutaneous Photo-Damage
Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.
research Skin Cancer: Understanding the Transformation from Conventional to Advanced Treatment Approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research Ayurveda-Based Botanicals as Therapeutic Adjuvants in Paclitaxel-Induced Myelosuppression
Asparagus racemosus and Withania somnifera can help reduce side effects of a cancer drug.
research Identification and Characterization of Four Immune-Related Signatures in Keloid
Four specific genes are linked to keloid formation and could be potential treatment targets.
research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
research Erosive Pustular Dermatosis of the Scalp: Clinicopathological Correlation Leading to a Definition of Diagnostic Criteria
Chronic scalp lesions with crusts and pus that heal with strong topical steroids suggest Erosive Pustular Dermatosis, confirmed by biopsy showing specific immune cells.
research Adenosine and Its Receptors in the Pathogenesis and Treatment of Inflammatory Skin Diseases
Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.
research Platelet-Rich Plasma by Single-Spin Process in Male Pattern Androgenetic Alopecia: Is It an Effective Treatment?
PRP treatment can improve hair density and thickness in male pattern hair loss, but better preparation methods are needed.
research The Impact of Chemotherapy on the Nutritional Status of Breast Cancer Patients
Chemotherapy worsens nutritional status in breast cancer patients, requiring targeted nutritional strategies.
research Inhibition of CISD1 Attenuates Cisplatin-Induced Hearing Loss in Mice via the PI3K and MAPK Pathways
Blocking CISD1 reduces hearing loss from cisplatin in mice.