research Spontaneous Tumor Regression in Keratoacanthomas Is Driven by Wnt/Retinoic Acid Signaling Cross-Talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
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research New Developments in the Molecular Treatment of Ichthyosis: Review of the Literature
New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.
research Ectodysplasin Signaling in Cutaneous Appendage Development: Dose, Duration, and Diversity
Ectodysplasin signaling is crucial for skin appendage development, requiring specific doses and durations.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research An Elevated Tumor Marker and Adrenarche in a Child Using Lavender Oil
Lavender oil use in a child may be linked to early puberty signs and elevated tumor marker levels.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research New Developments in Our Understanding of Acne Pathogenesis and Treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Lipoatrophy and Severe Metabolic Disturbance in Mice with Fat-Specific Deletion of PPARγ
Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
research BMP Signaling in the Control of Skin Development and Hair Follicle Growth
BMP signaling is crucial for skin and hair growth.
research Early Inductive Events in Ectodermal Appendage Morphogenesis
Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
research Dermal Fibroblasts in Cutaneous Development and Healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
research TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition
The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
research Wnt Signaling in Skin Organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
research Alopecia Secondary to Anti-Tumor Necrosis Factor-Alpha Therapy
Anti-TNF therapy can cause hair loss and skin issues.
research Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and Pilomatricoma
The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
research Defining the Localization and Molecular Characteristics of Minor Salivary Gland Label-Retaining Cells
The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
research Analysis of lncRNAs Expression Profiles in Hair Follicles of Hu Sheep Lambskin
lncRNAs may regulate hair follicle development in Hu sheep.
research Stem Cells in the Wild: Understanding Stem Cells Through Intravital Imaging
Intravital imaging helps us better understand stem cells in their natural environment and could improve knowledge of organ regeneration and cancer development.
research Evidence That Mirex Promotes a Unique Population of Epidermal Cells That Cannot Be Distinguished by Their Mutant Ha-ras Genotype
Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Mild Cutaneous Manifestation in Two Young Women with Extraordinary Hyperandrogenemia
Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.
research Identification of Differentially Expressed Genes in Actinic Keratosis Samples Treated with Ingenol Mebutate Gel
Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.
research Oral Contraceptive Pill Treatment Alters Gene Expression of Inflammatory Markers in Polycystic Ovary Syndrome Women
Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
research An Adolescent Girl with Coexisting Ovarian Mature Cystic Teratoma and HAIR-AN Syndrome, an Extreme Subtype of Polycystic Ovarian Syndrome
A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.
research Hair Loss Induced by Tumor Necrosis Factor Alpha Inhibitors
Some drugs used to treat immune conditions may cause different types of hair loss.
research Case 5: A Very Tall 7-Year-Old Boy with Medulloblastoma
A 7-year-old boy with a brain tumor developed early puberty, which was successfully treated with medication.
research Formulation Development, Pharmacological Evaluation, and Characterization of Eclipta Alba Phytosomes
Eclipta alba phytosomes improve bioavailability and therapeutic effects.
research Central Precocious Puberty Secondary to Peripheral Precocious Puberty Due to a Pineal Germ Cell Tumor: A Case and Review of Literature
A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.
research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration
3D-printed membranes with smart sensors can greatly improve tissue healing and have many medical applications.