77 citations
,
January 1989 in “Clinical Infectious Diseases” Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.
129 citations
,
November 2005 in “Internal Medicine Journal” This article reviews the recognition and management of Staphylococcus aureus toxin-mediated diseases, but it does not present new research findings.
37 citations
,
March 1990 in “The Journal of Pediatrics” Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
4 citations
,
November 2021 in “Frontiers in endocrinology” This study systematically compared pediatric and adult Cushing's disease patients, revealing more severe and earlier-onset symptoms in males, and distinct gender-specific clinical manifestations.
4 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported that ELL is crucial for maintaining the proliferative capacity of the basal layer in human epidermal keratinocytes by stabilizing RNA polymerase II at the transcription start site.
May 1993 in “Current problems in dermatology” This review discusses diagnostic approaches for childhood skin diseases with fever through clinical observations and covers recent advances in understanding the pathogenesis and epidemiology of related infections, without reporting new clinical results.
January 1982 in “Journal of The American Academy of Dermatology” Experts discussed treatments for skin conditions in children, emphasizing hydration, cautious medication use, and early intervention for infections.
66 citations
,
October 1984 in “Annual Review of Microbiology” This article reviews historical and recent developments related to toxic shock syndrome (TSS), emphasizing the increase in cases among young women using tampons, and calls for new research tools but does not report new results.
5 citations
,
May 2008 in “Annals of saudi medicine/Annals of Saudi medicine” This case report from India observed that short-term cabergoline treatment brought clinical and biochemical remission in a 12-year-old with persistent Cushing disease after surgery and radiotherapy.
6 citations
,
July 1990 in “The Journal of Pediatrics” A boy with toxic shock syndrome had severe heart rhythm problems but recovered with treatment.
December 2024 in “Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy)” This study found that vernalization treatment enhanced flowering and true shallot seed production across several shallot genotypes, suggesting it as an effective strategy for increasing shallot yields in highland areas.
176 citations
,
August 1981 in “JAMA” This study reported that toxic shock syndrome, originally noted in children, is now predominantly associated with menstruating women, with some experiencing recurrence and complications like vocal cord paralysis and impaired finger sensation.
58 citations
,
February 2013 in “Journal of Biological Chemistry” This study identifies specific molecular components involved in the intracellular trafficking of LGR5, revealing mechanisms that differ from typical GPCR recycling processes.
24 citations
,
October 2018 in “Addiction Biology” This study found that alcohol dependence is associated with altered HPA axis functioning, with AD patients showing higher hair cortisol concentrations and reduced ACTH and cortisol levels, irrespective of childhood maltreatment history.
44 citations
,
September 2014 in “Cell Death & Differentiation” This review discusses the role of tumor suppressors in controlling tumor-associated inflammation and suggests that targeting this inflammation may counteract the effects of tumor suppressor loss.
21 citations
,
June 2016 in “Genesis” This study identified a gene expression signature in mouse embryonic dermal fibroblasts that depends on Wnt/β-catenin activity, potentially influencing dermal fibroblast identity and function.
14 citations
,
January 2014 in “Cells Tissues Organs” This study found that single high-dose irradiation in mice induced more severe acute skin injury and hair depigmentation, while fractional doses led to longer-term damage in the dermis and subcutis.
7 citations
,
October 2019 in “Evidence-based Complementary and Alternative Medicine” This meta-analysis found that traditional Chinese medicine may be an effective and safe adjuvant therapy for androgenetic alopecia, improving efficacy rates and symptom scores compared to conventional medicine.
This study found that the human hairline is closely linked to several cranial, cerebral, and vascular structures, enabling precise localization of key neuroanatomical landmarks, which could assist in planning neurosurgical procedures.
5 citations
,
January 2015 in “Journal of clinical & experimental dermatology research” This study found that the MorrF topical solution combination showed significantly better hair growth improvements than Minoxidil alone in male patients with Androgenetic Alopecia.
191 citations
,
September 2011 in “Cell stem cell” This study found that polycomb-group-mediated repression plays a key role in regulating hair follicle stem cell states and lineage progression by distinct mechanisms in adult mouse skin.
176 citations
,
June 2017 in “Sexual Medicine Reviews” This review discusses the increasing prevalence of erectile dysfunction in young men and emphasizes the importance of identifying specific causes for effective management, reporting no new clinical results.
173 citations
,
January 2014 in “Nature Cell Biology” This study found that Wnt signalling activates hair follicle fate in hair follicle stem cells by relieving TCF3/4–TLE-mediated repression, with β-catenin being crucial for this process.
159 citations
,
July 2006 in “Endocrine Reviews” This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
139 citations
,
December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
98 citations
,
June 2001 in “Journal of biological chemistry/The Journal of biological chemistry” This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.
96 citations
,
June 2017 in “Nature Communications” This study identified WNT10A as crucial for adult epithelial cell proliferation and differentiation, suggesting β-catenin pathway activation may help address regenerative defects in WNT10A mutation patients.
86 citations
,
August 2011 in “Toxicological sciences” In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.
85 citations
,
October 2015 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that NF-κB signaling may connect injury response to regenerative processes in zebrafish hearts, potentially aiding the development of cardiac regenerative therapies in humans.
84 citations
,
October 2014 in “PLoS Genetics” This study found that epidermal Wnt production is crucial for forming the skin's spinous layer through a BMP-FGF signaling cascade, although Wnt from basal cells is not needed for their differentiation.