January 2025 in “Fitoterapia” This study reviewed literature on signaling pathways and concluded that these pathways are crucial pharmacological targets, influencing the mechanisms of drugs used in neurological, cardiovascular, and oncological treatments to correct signal transmission disturbances.
December 2024 in “arXiv (Cornell University)” In this study, researchers devised a stochastic hair growth model influenced by regular haircuts, using a process that undergoes linear growth subject to random resets, and used it to theoretically determine an ideal haircut routine.
December 2022 in “GS Publishing Services eBooks” This publication compiles scientific articles from diverse researchers and practitioners across Europe and other regions but provides no new research results.
This thesis found that desmoplakin mutations in cardiocutaneous syndrome are linked to dose-dependent disease severity and identified mechanisms by which KLHL24 mutations cause cardiomyopathy, with rescue experiments successfully preventing this phenotype in patient-derived heart tissues.
In this study, cepharanthine and tetrandrine demonstrated efficacy against SARS-CoV-2 in a cell-based infection assay, with cepharanthine showing a lower IC50 value.
This review found that antimalarial agents were more effective than steroids for Lichen planopilaris, while finasteride and dutasteride showed favorable impacts on frontal fibrosing alopecia, despite heterogeneous study quality.
November 2016 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)” This study found that Dendrobium sabin flower extracts, especially the methanolic one, demonstrated strong antioxidant and anti-aging properties without significant toxicity, suggesting its potential in treating photo-induced skin aging.
This research suggests that plucked hair follicles may serve as a reliable surrogate tissue for tumor biopsies in drug development, based on a mouse model linking hair and tumor pharmacodynamic responses.
October 2004 in “European Neuropsychopharmacology” This article reviews studies on younger men using finasteride for hair loss, finding persistent sexual and nonsexual side effects like erectile dysfunction and depression, and reports lower neurosteroid levels in affected individuals.
November 1966 in “British Journal of Dermatology” This conference proceeding abstract provides no new research results, focusing only on event details from the British Association of Dermatology's Forty-Sixth Annual Meeting held in Oxford in 1966.
September 2005 in “Archives of Dermatological Research” Large prostate patients more likely to have hair loss.
3 citations
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March 2016 in “Practical radiation oncology” This paper reviews total skin electron therapy for mycosis fungoides and reports no new results; the authors focus on dose de-escalation's impact on toxicity and response rates.
1533 citations
,
October 2008 in “Endocrine reviews” This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.
1160 citations
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November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
532 citations
,
August 2011 in “Journal of the American Academy of Dermatology” This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.
522 citations
,
January 2001 in “Cancer investigation” This review describes the unique pharmacological profile and clinical applications of pegylated liposomal doxorubicin, emphasizing its role in Kaposi's sarcoma and recurrent ovarian cancer, but reports no new clinical results.
471 citations
,
October 2012 in “Cellular and Molecular Life Sciences” This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.
451 citations
,
March 2005 in “Endocrine Reviews” This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
441 citations
,
May 2008 in “British Journal of Pharmacology” This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.
438 citations
,
October 2010 in “Oncogene” This review discusses the role of keratins in epithelial cell stress protection and cancer, highlighting their potential as multifunctional regulators and diagnostic markers, without presenting new research findings.
434 citations
,
October 2003 in “PTR. Phytotherapy research/Phytotherapy research” This review discusses the use of natural products in cosmetic preparations for skin and hair care, but reports no new research results.
425 citations
,
January 2021 in “SN Applied Sciences” This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
397 citations
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February 2004 in “British Journal of Dermatology” This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.
391 citations
,
September 2015 in “Journal of Clinical Lipidology” This document extends previous recommendations by the National Lipid Association for managing dyslipidemia, focusing on lifestyle therapies, special patient groups, and strategies to enhance adherence and patient outcomes.
343 citations
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October 2015 in “Endocrine Practice” This review discusses the diagnostic criteria and management strategies for Polycystic Ovary Syndrome (PCOS) and highlights the need for comprehensive clinical assessment, but does not report new clinical findings.
320 citations
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December 2018 in “Frontiers in Immunology” This review explores how preconditioning mesenchymal stromal cells can impact their secretome's therapeutic potential in regenerative medicine, emphasizing immunomodulatory and regenerative functions, but provides no new clinical results.
316 citations
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June 2017 in “Stem Cell Research & Therapy” This review covers the potential of SVF and ADSC therapies in regenerative medicine and highlights the challenges of regulation and efficacy, without reporting new clinical results.
299 citations
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January 2018 in “Journal of Clinical Investigation” This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.
295 citations
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September 2006 in “Cell Cycle” This review discusses the role of the TOR pathway in aging and suggests that rapamycin could potentially target age-related diseases, but reports no new clinical results.