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RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

Current treatments for folliculitis decalvans include antibiotics, isotretinoin, and potential new therapies like botulinum toxin A and PRP.

Squaric acid dibutylester effectively treats alopecia areata.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.

The combined treatment effectively managed severe skin issues in Olmsted syndrome.

A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.

Immune cells might contribute to hair loss caused by a specific mutation.

A new genetic mutation in the TRPV3 gene causes Olmsted-like syndrome in a Mongolian family.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

Scientists found key proteins and genes that affect skin and hair health, and identified potential new treatments for hair loss, skin disorders, and wound healing.

A child with Olmsted syndrome showed mild improvement in hair and skin issues with treatment.

C-scores can help predict gain-of-function and loss-of-function mutations.

Fish oil improves skin health in people with diabetes and high cholesterol.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Hair follicle stem cells help skin heal and grow during stretching.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

Cannabinoids may help treat various skin conditions.

Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.