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Stem cell self-renewal is complex and needs more research for full understanding.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Skin fat helps with body temperature control and has other active roles in health.

Mutant mice help researchers understand hair growth and related genetic factors.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

TRH stimulates human hair growth and extends the hair growth phase.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.

The hair follicle is a great model for research to improve hair growth treatments.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Topical JAK inhibitors may help treat some skin conditions but need more research.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Raspberry ketone may help grow hair and improve skin elasticity.

Spiny mice are better at regenerating hair after injury than laboratory mice and could help us understand how to improve human skin repair.