1 citations
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December 2022 in “Journal of applied biological chemistry” This study found that TRP-hair essence significantly protected and improved the quality of human hair, particularly against heat stress, by enhancing cuticle health and maintaining hair color.
December 2023 in “Asian journal of beauty & cosmetology”
34 citations
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August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
June 2026 in “International Journal of Drug Delivery Technology” This review explores the potential of herbal therapies and modern delivery methods for managing premature hair greying, highlighting promising plant-based treatments and emphasizing the need for clinical trials to validate their effectiveness.
December 2025 in “Universal library of medical and health sciences.” This study analyzes contemporary theories and practices to understand key factors influencing the development of the examined phenomenon, proposing trends and practical applications for researchers and practitioners, while acknowledging study limitations and suggesting future research directions.
January 2022 in “Clinical dermatology open access journal” This review summarizes research on cannabinoids like CBD and THCV, reporting that they improve hair growth in patients with androgenetic alopecia when applied topically, with CBD showing a dose-dependent effect.
76 citations
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August 2018 in “International Journal of Cosmetic Science” This review discusses the use of Dermal Papilla cells as in vitro models for studying hair growth modulators, emphasizing their role in aiding the development of new hair treatments, but reports no new clinical results.
February 2026 in “Chinese Medicine” Natural products might help treat hair greying.
9 citations
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January 2005 in “Experimental dermatology” The researchers observed that normal murine hair follicles are direct targets for melatonin, with receptor expression varying throughout the hair cycle, suggesting melatonin's role in hair cycle control.
260 citations
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December 2012 in “Cold Spring Harbor Perspectives in Biology” This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
October 2025 in “Editora Pasteur eBooks” The abstract discusses the multidisciplinary nature and advancement of dermatology and aesthetic procedures within the health sciences, emphasizing the integration of diagnostic, corrective, preventive, and therapeutic approaches, but does not provide specific study results.
November 2023 in “Open Repository of the University of Porto (University of Porto)” This summary of a pharmacy internship reports on expanding scientific knowledge through diverse activities, including exploring diabetes medications for obesity treatment and discussing the role of nutritional supplements in geriatrics.
101 citations
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April 1994 in “Baillière's clinical endocrinology and metabolism” This review discusses the role of 5α-reductase enzymes in androgen action and related disorders, noting that their specific inhibitory drugs show promise for conditions like benign prostatic hypertrophy; it reports no new clinical results.
January 2023 in “International Journal of Trichology” In a case series, this study reported significant hair regrowth in both men and women with androgenetic alopecia using a topical hemp extract high in CBD, THCV, and CBDV over six months.
May 2020 in “Authorea (Authorea)” This review discusses the diverse functions and therapeutic potential of ectopic olfactory receptors throughout the body, emphasizing their roles in various cellular processes and potential in cancer detection and therapy, but reports no new clinical results.
May 2025 in “Scientific Reports” This study found that geraniol, derived from Apiaceae plants, may be an effective and eco-friendly treatment for scabies, achieving complete clinical recovery in infected rabbits within two weeks.
112 citations
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May 2019 in “Pharmacological Research” This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.
August 2025 in “Fabad Journal of Pharmaceutical Sciences” This review highlights the potential medicinal benefits of Cuscuta reflexa, a parasitic plant known for its bioactive compounds, while emphasizing the need for further research to fully understand its therapeutic mechanisms and integrate its use into mainstream medicine.
18 citations
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February 2015 in “Acta Crystallographica Section D: Structural Biology” This study reports that Ca 2+ binding alters the dynamics and surface properties of PKD-like domains in Clostridium histolyticum collagenases, enhancing their stability and potentially aiding in collagen-targeting vehicle development.
January 2026 in “International Journal of Molecular Sciences” This review highlights brimonidine’s potential as a dermatological agent, noting its ability to improve rosacea-related facial redness and its effectiveness in various other skin conditions due to its vasoconstrictive and anti-inflammatory actions, with minimal systemic absorption and a favorable safety profile for long-term use.
1 citations
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January 2024 in “International journal of molecular sciences” This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.
32 citations
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May 2022 in “Frontiers in Pharmacology” This study proposes an AI-based method, DRGCC, using GraphSAGE and clustering constraints to predict associations between drugs and diseases, demonstrating reliable predictive performance that may aid drug repositioning efforts, including exploring drugs for COVID-19 treatment.
12 citations
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October 2023 in “International Journal of Molecular Sciences” This review examined the pathological effects of mechanical pressure on human skin at the cellular level, highlighting how various skin cell types respond to pressure, potentially leading to pathological changes such as inflammation, ischemia, and impaired differentiation.
13 citations
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December 2009 in “Journal of the Peripheral Nervous System” This laboratory study concluded that TRPA1 and TRPV1 channels do not play a role in mechanotransduction processes in slowly adapting type II mechanoreceptors in isolated rat sinus hair follicles.
12 citations
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March 2021 in “Journal of Investigative Dermatology” TRPM5 is crucial for maintaining hair growth.
February 2024 in “Genes to Cells” This study observed that tooth loss in mice led to premature graying of hair in the interbrow region, which was possibly due to reduced stimulation of the trigeminal nerve, suggesting that decreased mastication could cause this type of hair graying.
September 2023 in “Cells tissues organs” In this study, researchers observed that in mice, as they age beyond 200 days, unusual curved hair follicles and increased white hairs emerge, indicating stem cell-related changes in keratinocyte and melanocyte characteristics, providing insights into hair aging processes.
January 2023 in “Figshare” This review discusses changes in hair follicle characteristics and stem cell dynamics as indicators of aging in mice, noting increased occurrences of white hairs and curved hair follicles at older ages.
January 2008 in “Linchuang pifuke zazhi” This study found that betamethasone increased tyrosinase activity and melanin content in amelanotic melanocytes from human hair follicles, suggesting a potential mechanism for glucocorticoid treatment in vitiligo.
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the latest findings presented at the 4th Intercontinental Meeting of Hair Research Societies, covering advances in hair follicle biology, genetic bases for hair disorders, and potential new therapeutic approaches, but it reports no original study results.