7 citations
,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that thymus transplantation in athymic mice resulted in T-cell-driven hair follicle depigmentation and loss, without multiorgan autoimmune disease, highlighting mechanisms of tissue-specific tolerance.
6 citations
,
October 2018 in “PLoS ONE” This study found that chronic stress may inhibit hair follicle growth and melanogenesis in mice through modulation of the central HPA axis, with C57BL/6 mice appearing most sensitive to these effects.
5 citations
,
March 2019 in “Scientific Reports” This study reports that the side population technique can isolate melanocyte stem cells from human hair follicles, potentially allowing them to be used for skin pigmentation repopulation.
4 citations
,
December 2024 in “Clinical Cosmetic and Investigational Dermatology” This study suggests that combining baricitinib with narrowband UV-B therapy is an effective and well-tolerated approach for treating active nonsegmental vitiligo.
4 citations
,
January 2021 in “Journal of Clinical Medical Research” This review provides an in-depth analysis of the structure and function of c-kit activation, and its role in both normal physiological and pathological conditions, with no new research findings reported.
4 citations
,
January 2015 in “Hair therapy & transplantation” This review discusses melanocyte stem cells in hair follicles and their potential role in cell-based therapy for vitiligo, reporting no new experimental results.
2 citations
,
January 2018 in “The Korea Journal of Herbology” In this study with C57BL/6 mice, SHJ extract was associated with increased hair growth and density, suggesting potential use in hair care cosmeceuticals, while also enhancing melanin production in melanoma cells.
2 citations
,
January 2017 in “Journal of Pigmentary Disorders” This study explores the complex and not yet fully understood causes of premature hair greying, noting genetic factors such as Pax3 and MITE genes, potential defects in melanin transfer, and associations with certain syndromes, while stating that effective treatments are currently lacking.
1 citations
,
January 2025 in “Frontiers in Pharmacology” This review discusses the therapeutic and pharmacological potential of total glucosides of paeony in dermatological treatment and notes the need for more rigorous scientific studies.
1 citations
,
September 2024 in “Quality in Sport” This review explores the complex biological process of hair graying, highlighting oxidative stress, genetic factors, and interventions like antioxidants and genetic therapy as key aspects affecting the preservation of hair pigmentation.
1 citations
,
July 2016 in “Elsevier eBooks” Understanding skin structure and development helps diagnose and treat skin disorders.
1 citations
,
September 2013 in “Elsevier eBooks” This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.
June 2026 in “International Journal of Drug Delivery Technology” This review explores the potential of herbal therapies and modern delivery methods for managing premature hair greying, highlighting promising plant-based treatments and emphasizing the need for clinical trials to validate their effectiveness.
February 2026 in “Chinese Medicine” Natural products might help treat hair greying.
January 2026 in “Asian Journal of Pharmaceutical and Clinical Research” This review discusses the potential of umbilical cord blood and umbilical cord-derived stem cells in treating various chronic diseases by highlighting their regenerative abilities and ethical advantages as well as the translational challenges and clinical implications.
January 2026 in “International Journal of Dermatology Venereology and Leprosy Sciences” This study suggests that metformin's ability to enhance insulin sensitivity may improve acanthosis nigricans by addressing the underlying insulin resistance.
This study highlights that azelaic acid, initially recognized for skin hypopigmentation, shows potential in treating various skin conditions due to its complex mechanisms, even though these are not yet fully understood, indicating a need for further research.
August 2025 in “Aesthetic Cosmetology and Medicine” In this article, researchers explored how blue light exposure affects the scalp and hair follicles, highlighting oxidative stress and hair growth disruptions, while emphasizing the importance of protective strategies like antioxidants and limiting light exposure.
April 2025 in “International Journal of Ayurveda and Pharma Research” This case study described the use of Ayurvedic treatments, including internal medications and external applications, which resulted in black hair growth, increased hair density, and reduced hair fall in a 28-year-old woman with premature graying.
January 2025 in “American Journal of Stem Cells” This review discusses the role of melanocyte stem cells in skin pigmentation and potential regenerative therapies, but reports no new clinical results.
November 2024 in “International Journal of Agricultural Invention” This review highlights the therapeutic properties and nutritional value of amla (Phyllanthus emblica), noting its high vitamin C content and diverse pharmacological activities, including antidiabetic and antioxidant effects, as evidenced in traditional medicine practices.
January 2024 in “International Journal of Herbal Medicine” This abstract describes the role of melanin in determining hair color and protecting against UV radiation, highlighting how its production affects hair health, growth, and vitality, with reduced production contributing to greying with age.
September 2023 in “Journal of microbiology and biotechnology” This study found that low molecular weight collagen peptide from fish may promote hair growth in both human cells and mice by activating the Wnt/β-catenin signaling pathway.
August 2023 in “International journal of research in medical sciences” In this study, application of Revgrey® hair serum was found to be safe and may offer some benefit in treating premature greying of hair, with slightly to moderately increased hair recovery observed in a small group of patients after 12 weeks.
August 2023 in “Research Square (Research Square)” In this study, researchers observed that Melan A, a melanocytic marker, was significantly expressed in hair follicles of alopecia areata patients and correlated with immune infiltrates, suggesting melanocytes might contribute to the autoimmune response in this condition.
December 2021 in “Dermatology research” This study found that individuals with premature graying of hair had significantly lower serum levels of vitamin B12, ferritin, and calcium compared to those without premature graying.
This review reports the first known case of hair repigmentation associated with lamivudine use and examines mechanisms related to drug-induced hair repigmentation, suggesting potential therapeutic strategies for reversing hair graying.
324 citations
,
May 2002 in “Oncogene” 7 citations
,
August 2023 in “Frontiers in Immunology” This review discusses the role of transient receptor potential channels in pathological scarification and suggests these channels as potential targets for its prevention and treatment, although it reports no new clinical findings.
9 citations
,
January 2017 in “Annals of Dermatology” In this study of a TRPS type I patient, many genes related to keratin and hair development were down-regulated in balding scalp areas, providing new insights into TRPS and hair morphogenesis.