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Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Minoxidil improves blood flow in heart failure patients.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

Keratins are important for skin cell health and their problems can cause diseases.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.

The document concludes that surgery is a preferred treatment for cicatricial alopecia, with the method chosen based on individual factors and may require multiple sessions and careful postoperative care.

Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.

Skin fat plays a key role in immune defense and healing beyond just storing energy.

These skin conditions in African men need combined medical treatments and lifestyle changes.

Artificial sebum L closely mimics human sebum for drug delivery research.

Alopecia areata is an unpredictable autoimmune hair loss condition, treated based on severity, with half of patients regrowing hair within a year without treatment.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Polyamines help fix DNA damage accurately in cells.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Melatonin improved mental health and metabolism in women with PCOS.

Using sharp tools and the right techniques in hair transplant surgery leads to less damage to hair follicles.