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The three-layer microneedle system effectively delivers minoxidil into the skin, showing potential as a safe and efficient treatment for hair loss.

The UV–Vis Spectrophotometry method effectively measures minoxidil in rat skin for alopecia treatment.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Plant-based compounds can improve wound dressings and skin medication delivery.

Advanced human skin models improve drug development and could replace animal testing.

Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.

New scaffold materials help heal severe skin wounds and improve skin regeneration.

FT-Raman spectroscopy is effective for identifying drug polymorphs, ensuring quality and stability.

ADSCs help in wound healing and skin regeneration but need more research for full understanding.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Hydrogel composites have great potential in regenerative medicine, tissue engineering, and drug delivery.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

The document concludes that immune system abnormalities cause alopecia areata, but the exact process is still not completely understood.

Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.

Electrospun scaffolds can improve healing in diabetic wounds.

Pulsed dye laser and hydrogel dressings effectively treat hypertrophic scars.

The letters discussed medical tools, costs, treatment efficacy, and patient care complexities.

Inorganic-based biomaterials can quickly stop bleeding and help wounds heal, but they may cause issues like sharp ion release and pH changes.

A new type of amniotic tissue graft improves wound healing better than other grafts.

Metformin might help treat certain skin conditions, but more research is needed.