23 citations
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March 2010 in “Actas Dermo-Sifiliográficas” In this study, early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid atherosclerosis compared to controls, suggesting cardiovascular screening might be beneficial for this group.
22 citations
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January 2019 in “Hormone and Metabolic Research” This meta-analysis confirmed associations between some androgenic and metabolic parameters in women with PCOS, suggesting that these measurements might help predict metabolic risk in this population.
21 citations
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September 2019 in “Archives of Physiology and Biochemistry” In this study, HIIT increased adiponectin levels and improved cholesterol profiles in women with PCOS, but did not change leptin or vaspin levels.
19 citations
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November 2012 in “Journal of Dermatological Treatment” In this study, isotretinoin treatment in women with severe acne increased body weight and triglycerides but did not affect androgens or insulin sensitivity.
18 citations
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January 2000 in “Food Science and Technology Research” In this study, partially purified apple polyphenols were found to inhibit preadipocyte differentiation in mouse cells by reducing GPDH activity and triglyceride accumulation.
18 citations
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July 2019 in “Clinical Endocrinology” The researchers reported that among Mediterranean Sicilian women with PCOS, Phenotype B exhibited the most severe metabolic abnormalities, notably obesity and altered glucose metabolism, whereas Phenotype D showed no such issues.
17 citations
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December 2011 in “Journal of the European Academy of Dermatology and Venereology” People with vitiligo may have a lower risk of heart disease.
16 citations
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January 2014 in “International Journal of Trichology” This study found that male Indian patients under 30 with early androgenetic alopecia were more likely to have metabolic syndrome compared to age-matched controls.
15 citations
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October 2016 in “Journal of The European Academy of Dermatology and Venereology” This meta-analysis found that patients with androgenetic alopecia have significantly abnormal lipid profiles, which could contribute to the link between this condition and cardiovascular diseases.
15 citations
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May 2022 in “Fermentation” This study found that fermented camel milk containing 50% pumpkin seed milk significantly improved oxidative stress markers in rats and enhanced sensory and physicochemical properties compared to untreated groups.
14 citations
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March 2016 in “Journal of Dermatology” This study found that Korean patients with androgenetic alopecia had higher rates of cardiovascular diseases and related risk factors than those without the condition, with variations by severity and type of hair loss.
14 citations
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November 2021 in “Nanoscale” This study's simulations revealed the complex "onion-like" organization of a lipid nanoemulsion droplet containing vitamins A and E for skin delivery, showing distinct concentration patterns of these vitamins within different layers of the nanodroplet.
14 citations
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September 2014 in “Journal of Pediatric and Adolescent Gynecology” This study found that irregular menstrual cycles in Brazilian adolescents were significantly associated with a higher occurrence of metabolic syndrome and polycystic ovary syndrome indicators.
13 citations
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December 2011 in “Korean Journal of Food Science and Technology” This study suggests that black soybean extract promotes hair growth and improves scalp health by enhancing blood circulation and cellular proliferation, although further human studies are needed to verify these effects.
12 citations
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January 2022 in “International Journal of Clinical Practice” This study found that women with PCOS, especially those who are obese, showed higher oxidative stress and decreased antioxidant levels, correlating with metabolic syndrome and cardiovascular disease risk factors.
12 citations
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January 2010 in “Acta Dermato Venereologica” In this case-control study, female patients with early onset androgenetic alopecia had higher triglycerides, total cholesterol, and LDL-C levels, and lower HDL-C levels compared to females with other skin diseases.
11 citations
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January 2017 in “Journal of Endocrinology/Journal of endocrinology” This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.
10 citations
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April 2015 in “Netherlands Heart Journal” This study concluded that there is no association between male pattern baldness and the severity or presence of coronary artery disease as measured by Gensini and Rentrop scores.
10 citations
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November 2011 in “The Journal of Clinical Endocrinology & Metabolism” This study suggests that a lifestyle program incorporating nutrition education, exercise, and behavior therapy can improve reproductive and metabolic outcomes in some obese teenage girls with PCOS who successfully lose weight.
9 citations
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April 2023 in “World Journal of Clinical Cases” Test liver enzymes and triglycerides every 5-6 months, and cholesterol levels in the first two months for acne patients on isotretinoin.
8 citations
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March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study of healthy men, low levels of testosterone and dihydrotestosterone were associated with higher body mass index, fat content, and insulin resistance, but their effects on lipid and glucose metabolism were similar in quality.
8 citations
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April 1990 in “Hormone and Metabolic Research” This study found that a combination of cyproterone acetate and ethinyl estradiol over one year did not affect glucose tolerance but increased total cholesterol, HDL cholesterol, and triglycerides in patients with moderate hyperandrogenism.
7 citations
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August 2019 in “Journal of Ovarian Research” This study reported that both phlebotomy and oral contraceptive pills with cyproterone acetate effectively improved insulin resistance and androgenic profiles in women with PCOS, but OCs had more impact on regularizing menstrual cycles.
7 citations
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May 2019 in “Journal of the Formosan Medical Association” This study found that overweight women with polycystic ovary syndrome carrying the HSD3B1 1245C allele had an increased presence of female pattern hair loss compared to those with the wild-type genotype.
7 citations
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January 2022 in “Evidence-based complementary and alternative medicine” This study found that ginger supplementation significantly improved persistent hypothyroid symptoms and may aid in weight and lipid profile management in hypothyroid patients with normal TSH levels.
7 citations
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February 1962 in “Experimental Biology and Medicine” This study observed that male and female epidermis differ significantly in total lipid and phospholipid levels during different stages of the hair growth cycle.
6 citations
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January 2020 in “The Aging Male” In this study, five-year testosterone replacement therapy improved fasting blood sugar, HbA1c, and triglyceride levels in Japanese hypogonadal men without significantly affecting prostate-specific antigen levels.
6 citations
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November 1960 in “Experimental Biology and Medicine” In this study, despite morphological differences in the hair growth cycle stages, the lipid composition of the epidermis and dermis showed no significant variation, though water content and cholesterol levels differed between these skin layers.
6 citations
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January 2015 in “International journal of reproduction, contraception, obstetrics and gynecology” In this study, metabolic syndrome was common among women with polycystic ovarian syndrome, with a significant association with higher BMI and prevalent dyslipidemia.
5 citations
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October 2021 in “Journal of Ovarian Research” This review indicates promising potential for cinnamon supplementation to improve metabolic outcomes in PCOS, but more clinical trials with higher doses and longer durations are needed to confirm these effects.