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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Apple polyphenols, especially from unripe apples, can help prevent cells from turning into fat cells.

Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.

People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.

Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Emu oil may slow down skin healing but increases hair growth in burn wounds.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.

Vegetarians should take B vitamin supplements to avoid health issues.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Microemulsions could improve how drugs are delivered and absorbed in the body.

Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

Cinnamon can help manage symptoms of polycystic ovary syndrome, improve menstrual cycles and fertility, and positively affect cholesterol and blood sugar levels, but more research is needed to confirm these effects and find the best dosage.

Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).

Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.

Zinc is crucial for skin health and treating various skin disorders.

Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.

Curcumin improved some metabolic factors in women with PCOS but did not affect cholesterol, insulin, or testosterone levels.

Women with PCOS have higher xanthine oxidase activity linked to inflammation and heart disease risks.

A cat with skin bumps and itching had high blood fats and skin infections, which improved with diet and medication changes.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.