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The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.

Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.

Young women with PCOS and no other heart risk factors have normal heart function.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

The document concludes that a high-protein, low-carb diet can lead to significant weight loss but requires caution and further research.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

A new mutation in the AGPAT2 gene causes severe fat tissue loss and related health issues by reducing the protein's levels.

Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.

Older women often have vulva issues due to less estrogen, which can be misdiagnosed and lead to wrong treatments.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.

AGA risk factors include age, smoking, hypertension for men, and age, dyslipidemia for women; lifestyle changes may help prevention.

Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.

Lower vaspin levels in the blood may indicate a better response to fertility treatment in women with PCOS.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

People with early hair loss may have a higher chance of enlarged prostate and metabolic syndrome, so they should be checked for urinary and metabolic issues.

A patient with Werner syndrome showed a range of aging-like symptoms and metabolic issues, underscoring the need for early detection and treatment.

Researchers identified genes and proteins that may influence wool thickness in sheep.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Darkened knuckles can be an early sign of insulin resistance.

Chinese women with PCOS have higher androgen levels, which change with age and weight.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Acne in reproductive-age women may be linked to conditions like PCOS and lifestyle factors, so doctors should check for these when treating acne.

Model improves accuracy in predicting hair loss effects.

Premature hair greying may indicate a higher risk of metabolic problems.