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In this study of healthy men, low levels of testosterone and dihydrotestosterone were associated with higher body mass index, fat content, and insulin resistance, but their effects on lipid and glucose metabolism were similar in quality.

In this study, despite morphological differences in the hair growth cycle stages, the lipid composition of the epidermis and dermis showed no significant variation, though water content and cholesterol levels differed between these skin layers.

This study found that patients with androgenic alopecia exhibited higher levels of Malassezia colonization and altered sebum composition compared to individuals without AGA.

This study observed that in Japanese females, hair lipid composition showed significant correlations, suggesting CH and CERs may act as a barrier against sebum-derived lipids.

This study observed that male and female epidermis differ significantly in total lipid and phospholipid levels during different stages of the hair growth cycle.

This study found that the lipid composition of the epidermis varies significantly throughout the hair growth cycle and after applying methylcholanthrene, with notable differences observed between hyperplastic and carcinomatous conditions.

This study found that combining an oral herbal composition with a topical hair tonic resulted in a stronger hair growth effect in mice than either treatment alone.

This study suggests that both the sebum composition and microbial imbalance on the scalp may play a role in the development of androgenetic alopecia among Japanese males.

In this study, female-to-male transsexuals treated with long-acting testosterone undecanoate experienced an increase in lean mass but no change in fat mass or bone mineral density over 24 months.

Different oils affect hair flexibility and strength, with their impact varying on whether hair is virgin or bleached.

In this study, researchers observed that patients with androgenetic alopecia show differences in scalp microbial communities compared to the general population, including an increase in Cutibacterium acnes, particularly in males, which may interact with lipid and immune pathways to contribute to hair follicle miniaturization.

This study reported that antimicrobial and topical retinoid therapies led to significant changes in the lipid profiles of sebaceous follicular infundibulum, with increased triglycerides and ceramide subfractions observed.

This study investigated the effects of pathological α-synuclein on sebaceous gland cells in Parkinson's disease, finding that α-synuclein exposure altered cellular differentiation and lipid production, suggesting a potential link between α-synuclein and lipid dysregulation in the skin of PD patients.

This study found that supplementing cat and dog food with PUFA-rich oil improved hair flexibility, brightness, and skin condition, though it also increased serum triglyceride levels, suggesting careful consideration of dosage and fatty acid composition is warranted.

This review highlights that dysbiosis in skin and scalp microbiomes is linked to both atopic dermatitis and androgenetic alopecia, suggesting that microbial composition influences disease progression.

This study found that women with PCOS had higher body fat and worse insulin resistance than non-PCOS women, with body composition influencing metabolic profiles independently of PCOS status.

This study found that combining oral herbal composition with topical hair tonic in mice resulted in enhanced hair growth, improved blood antioxidant capacity, and reduced lipid peroxidation and triglyceride levels.

This study found that different diets had a negligible impact on guinea pigs' hair structure and did not significantly alter their health parameters, suggesting both tested diets met their nutritional needs without affecting their well-being.

This study found that in genetically diabetic mice, supplementation with safflower or evening primrose oil prevented the decrease in certain fatty acids and improved skin conditions, but increased plasma glucose levels.

This study found that in mice, deleting the keratin 10 gene enhances sebocyte differentiation and increases secretion of sebum and certain lipids without affecting proliferation-associated keratins.

This study found that women with polycystic ovary syndrome have higher global adiposity and increased visceral fat, particularly in the ip and mesenteric depots, compared to women without androgen excess.

This study found that berberine supplementation improved gut microbiota composition and reduced obesity-related hepatic inflammation and oxidative stress in genetically obese mice.

In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.

In this study, transgenic male mice over-expressing the androgen receptor in mesenchymal stem cells showed reduced fat mass and improved glucose clearance, suggesting enhanced androgen sensitivity may alter body composition.

This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.

This study reported that women with polycystic ovarian syndrome have higher serum irisin levels, which are associated with metabolic and hormonal imbalances, including hyperandrogenism, total cholesterol, and visceral fat.

This study found a significant correlation between lower triglyceride levels and reduced acne severity among medical students, while no significant association was observed between BMI and acne severity.

This study analyzed the composition and cost of 50 cosmetic body scrubs for keratosis pilaris, finding that chemical exfoliants with glycolic acid may reduce symptoms by enhancing skin shedding and reducing water loss, but further clinical studies are needed to confirm their effectiveness.

In this review paper, the authors explored the composition and role of lipids in human hair, highlighting their importance for hair texture, moisture retention, and tensile strength, while noting that the understanding of hair lipids' functions remains controversial and requires further research.

In this study, primary cilia were found to contribute to meibomian gland enlargement and lipid production, though they are not necessary for normal gland development.