1 citations
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February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” This study elucidates a mechanism for acne-like skin toxicity caused by EGFR/MEK inhibitors, involving an interaction with skin bacteria to trigger inflammation, which supports existing antibiotic treatment practices.
1 citations
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September 2013 in “Mayo Clinic Proceedings” This case study identified low iron stores, potentially linked to heavy menstrual periods, as a trigger for diffuse nonscarring alopecia in a 31-year-old woman, leading to a diagnosis of telogen effluvium, for which iron supplementation was prescribed.
This article provides physician associates with an evidence-based approach to diagnosing and treating alopecia, focusing on recognizing patterns, identifying triggers, and applying targeted interventions to improve patient outcomes in hair loss.
This source reports that telogenic hair loss, while not leading to complete baldness, significantly impacts patients' quality of life due to its effects on their psychoemotional state; no standardized treatment currently exists, so therapy focuses on addressing trigger factors and psychological well-being.
November 2025 in “Scientific Reports” In this study, researchers linked SARS-CoV-2 infection to telogen effluvium in some COVID-19 patients by observing the accumulation of viral proteins in hair follicle cells, which may trigger stress responses and cell death, suggesting hair follicles as a potential target in COVID-19.
September 2025 in “BioMed” In this case report and literature review, researchers observed that black hairy tongue syndrome can be improved by dietary restrictions and local care, identifying factors like antibiotics, malignancies, and certain medications as common triggers, with resolution achieved by eliminating these factors when possible.
August 2025 in “Cosmetics” This review discusses the possible link between cosmeceuticals and frontal fibrosing alopecia but reports no conclusive findings; the authors stress further research on environmental triggers is needed.
In this case report, the authors documented a fatal instance of Stevens-Johnson syndrome in an elderly woman potentially triggered by doxycycline and flucloxacillin, emphasizing the importance of recognizing such rare but severe drug reactions in older patients.
June 2025 in “British Journal of Dermatology” This report describes two unusual cases of frontal fibrosing alopecia in men, highlighting potential vaccine-related immune triggers and genetic factors, especially regarding the pronounced facial papular phenotype observed.
May 2025 in “Australasian Journal of Dermatology” In this observational study, researchers reported a significant association between COVID-19 infection or vaccination and the development of new-onset lichen planus, suggesting these events, particularly infection, may act as triggers for the condition.
March 2025 in “Meditsinskiy sovet = Medical Council” In this article, researchers explore the causes, diagnostic approaches, and treatment strategies for diffuse telogen alopecia, emphasizing the importance of identifying triggers such as stress and metabolic disorders to effectively manage this hair loss condition.
February 2025 in “Cureus” In this case report, a 31-year-old man developed erosive pustular dermatosis of the scalp after hair transplant surgery, highlighting potential surgical trauma as a trigger for this condition in younger patients.
February 2025 in “Journal of the European Academy of Dermatology and Venereology” This study found that epidermal growth factor receptor inhibitors can induce erosive pustular dermatosis of the scalp, typically appearing sooner and affecting the scalp more extensively compared to other triggers.
January 2025 in “Journal of Dermatology & Dermatologic Surgery” This study reports a unique case of identical twins experiencing alopecia areata at the same time, suggesting potential environmental triggers for this polygenic autoimmune condition.
December 2024 in “Journal of Clinical Medical Research” This study explores regenerative medicine's potential to improve quality of life, especially in aging populations, by examining key components like triggering agents, potentiators, and additives, and how their combined use may accelerate tissue repair through a strategy called stacking.
December 2024 in “Clinical Cosmetic and Investigational Dermatology” This study reports that vitiligo prevalence in a Saudi cohort is similar to global figures, with stress as a common trigger, frequent lesional pruritus, and widespread thyroid issues and low vitamin D levels.
March 2024 in “CRC Press eBooks” In this study, telogen effluvium is characterized as a common condition in women involving sudden hair shedding due to hair follicles prematurely entering the telogen phase, with potential triggers including fever, childbirth, and stress.
September 2023 in “Forum Dermatologicum” This source discusses androgenetic alopecia, noting that male patients may transition from topical minoxidil to its systemic form or from finasteride to dutasteride for potentially better results, while female patients might require extensive lab testing to identify hyperandrogenism due to environmental triggers.
This study used data mining of the FDA Adverse Event Reporting System to analyze drug-induced pruritus, revealing differences in gender, age, and weight among cases, and identified ophthalmic drugs and systemic antibacterials as common triggers, contributing to potential prevention and treatment strategies for pruritus.
This review discusses how nanotechnology can potentially enhance the treatment and delivery of clomiphene citrate for ovulatory disorders, with a focus on improving solubility and minimizing side effects in women experiencing anovulatory infertility, highlighting its 80% efficacy in triggering ovulation in treated cases.
April 2023 in “Journal of Investigative Dermatology” In this study using a mouse model of Pemphigus vulgaris, researchers found that loss of desmoglein 3 adhesion in hair follicle stem cells triggers a regenerative program restoring stem cell function, requiring Hedgehog pathway suppression.
January 2023 in “Indian dermatology online journal” This case study highlights that sarcoidosis lesions can occur following hair removal by waxing, emphasizing the need to consider superficial traumas as potential triggers for cutaneous sarcoidosis.
December 2022 in “Exploratory animal and medical research” This study found that acral lick dermatitis in dogs has a higher prevalence in young male dogs, especially Labrador retrievers, during colder months, with psychogenic triggers being the most common cause.
September 2021 in “CRC Press eBooks” This review discusses erosive pustular dermatosis of the scalp, including its characteristics, potential triggers, and its classification as a neutrophilic dermatosis, but reports no new clinical findings.
January 2018 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” This study observed that stress, as indicated by hair cortisol concentrations, may trigger onset of hair loss in alopecia areata, although the findings were not statistically significant.
January 1995 in “Equilibrium Research” This study suggests that supporting cells are the origin of regenerated hair cells in the avian basilar papilla, with epidermal growth factor as a potential trigger, and indicates a possibility of hair cell regeneration in mammalian vestibular epithelia.
143 citations
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September 1991 in “Archives of Dermatology” In this study, patients with generalized pustular psoriasis were classified into subgroups to better understand the disease's variability and assist in treatment selection, highlighting the role of localized infections in triggering flares.
127 citations
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January 2013 in “PLOS ONE” This study found that feeding aged mice a probiotic yogurt induced changes leading to thicker, healthier fur, suggesting a bacteria-triggered interleukin-10-dependent mechanism that mimics signs of youth and reproductive fitness.
87 citations
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March 2017 in “Journal of Clinical Investigation” In this study, researchers identified PSENEN mutations that can lead to a form of Dowling-Degos disease, characterized by follicular hyperkeratosis and an increased susceptibility to acne inversa, especially in the presence of certain trigger factors.
66 citations
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March 2009 in “British journal of surgery” This review discusses hidradenitis suppurativa's pathogenesis, including its inflammatory nature and the role of smoking as a triggering factor, but reports no new clinical results.