24 citations
,
December 2016 in “Stem Cell Research & Therapy” This study found that P311 triggers transdifferentiation of epidermal stem cells into myofibroblast-like cells via TGFβ1/Smad signaling during wound healing.
1 citations
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May 2022 in “Archiv Euromedica” This report discusses a case where pregnancy triggered the development of folliculitis decalvans, highlighting that systemic treatments are typically avoided during pregnancy in favor of topical medication.
July 2025 in “International Journal of Pharmacognosy and Pharmaceutical Sciences” This review discusses acne's common triggers, challenges with conventional treatments, and the potential of alternative therapies to reduce side effects and enhance outcomes, highlighting an increasing interest in safer approaches due to the limitations of current topical options.
This case report explores a 28-year-old man with type 2 diabetes who experienced telogen effluvium, a type of hair loss, following treatment for euglycemic diabetic ketoacidosis with luseogliflozin, possibly triggered by physical stress related to his condition and treatment.
4 citations
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September 2012 in “Transplant international” Graft rejection in a hand transplant may trigger hair loss due to autoimmune responses.
This study reports that COVID-19 can trigger various dermatological autoimmune and autoinflammatory diseases, highlighting the need for clinicians to consider these potential connections during the pandemic.
April 2021 in “International journal of advanced research” This study found that Covid-19 may trigger autoimmune pathways leading to alopecia areata and telogen effluvium, highlighting a connection that warrants further investigation.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.
November 2001 in “CRC Press eBooks” This article discusses how metabolic imbalances can trigger telogen effluvium by causing hair follicles to prematurely enter the shedding phase, and includes no new research findings.
236 citations
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April 2015 in “Cell” This study found that patterned hair plucking in mice triggers a collective regeneration response in nearby unplucked hair follicles via a quorum sensing mechanism involving immune signaling.
27 citations
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September 2021 in “Microbiology Spectrum” This study found that multimetal starvation by the immune protein calprotectin triggers unique regulatory responses in Pseudomonas aeruginosa, beyond those seen with individual metal shortages.
11 citations
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May 2011 in “Journal of Cutaneous Medicine and Surgery” This report describes a case of lichen planopilaris potentially triggered by chronic scalp trauma from break dancing, emphasizing the need for careful examination to differentiate it from androgenetic alopecia.
4 citations
,
November 2024 in “International Journal of Molecular Sciences” This review explores whether SARS-CoV-2 could trigger or worsen α-synucleinopathies, like Parkinson's disease, by affecting α-synuclein misfolding and aggregation, potentially linking COVID-19 with the development of parkinsonism-like symptoms.
2 citations
,
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.
1 citations
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September 2025 in “PLoS ONE” This study identified numerous drugs with potential to trigger vitiligo, cautioning that these pharmacovigilance findings need further validation and that patients on these medications should be monitored for vitiligo development.
1 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.
December 2025 in “Indian Journal of Case Reports” This case report highlights an unusual instance of azathioprine potentially triggering rapid alopecia areata and bone marrow suppression in a patient with chronic spontaneous urticaria, with improvement seen after stopping the drug.
November 2025 in “PLoS ONE” This study found that synthetic RNA and DNA trigger significant increases in certain chemokines in human keratinocytes, predominantly via NF-κB activation, without evidence of alternative splicing, suggesting other regulatory pathways may be involved.
March 2024 in “Cell communication and signaling” This study found that sleep deprivation in mice can trigger prostatitis by activating the cGAS-STING pathway due to reduced levels of dihydrotestosterone and melatonin, resulting in a pro-inflammatory environment, while recovery sleep can mitigate these effects.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that tissue damage in adult mice triggers the release of mitochondrial DNA, which activates the TLR9 pathway and influences hair regeneration by recruiting gamma delta T cells, ultimately affecting healing outcomes such as fibrosis.
April 2016 in “Journal of Investigative Dermatology” This study found that inhibiting JAK signaling can unexpectedly trigger hair growth in resting-phase mouse skin, implicating JAK-STAT pathways and oncostatin M in maintaining hair follicle stem cell quiescence.
January 2015 in “Durham e-Theses (Durham University)” This study found that glucose starvation and hypoxia are physiological triggers of ER stress in in vitro differentiated adipocytes, rather than high concentrations of saturated fatty acids, cholesterol, or proinflammatory cytokines.
219 citations
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January 2005 in “Plastic & Reconstructive Surgery” This study found that surgical deactivation of migraine headache trigger sites can significantly reduce migraine symptoms, with 92% of patients reporting at least a 50% reduction in migraine frequency, duration, or intensity.
191 citations
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December 2013 in “Plastic & Reconstructive Surgery” This study found that surgical deactivation of migraine trigger sites significantly reduced or eliminated migraine symptoms in most treated patients, compared to controls, and also decreased migraine-associated costs and workdays lost.
57 citations
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May 2007 in “Nature” This study suggests that wounding skin in adult mice can trigger new hair follicle formation, indicating mammalian skin may have greater regenerative capacity than previously thought.
50 citations
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August 2019 in “Cell Communication and Signaling” This study identifies NFAT5 as a crucial transcription factor necessary for triggering innate immune responses in the blood vessel lining that lead to atherosclerosis under hypertonic stress conditions.
44 citations
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January 2021 in “Dermatologic Therapy” This study suggests that COVID-19 infection may trigger telogen effluvium, a condition of hair shedding, though medication side effects and pandemic-related stress cannot be excluded as contributing factors.
27 citations
,
April 2005 in “Journal of Chemotherapy” This study reported two cases of alopecia universalis triggered by PEG-interferon and ribavirin therapy for chronic hepatitis C, with hair regrowth observed after therapy completion or withdrawal.
14 citations
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July 1987 in “Contact Dermatitis” This article describes cases of allergic contact dermatitis triggered by minoxidil but provides no new clinical findings.
9 citations
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March 2017 in “JAAD Case Reports” This case report describes erosive pustular dermatosis of the scalp triggered by contact dermatitis from a glued-on hair piece, marking the first instance of this specific cause.