December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study describes alopecia areata as a long-term, immune-mediated disorder characterized by non-scarring hair loss, often occurring in genetically predisposed individuals and possibly triggered by T-cell-mediated inflammation, environmental stressors, and genetic factors.
December 2025 in “Skin Appendage Disorders” This case report, one of the youngest on record, suggests that systemic stress might trigger pediatric sudden hair graying linked with diffuse alopecia areata, emphasizing the need to differentiate it from congenital silvery hair syndromes due to their distinct prognosis and treatment options.
December 2025 in “SKINdeep” This paper reviews existing studies on the role of environmental humidity in skin health, highlighting that low humidity can impair the skin's barrier function and trigger inflammatory responses, though the precise mechanisms remain to be fully explored.
September 2025 in “Journal of Veterinary Cardiology” This study observed that a 13-month-old cat experienced transient myocardial thickening and congestive heart failure episodes likely due to minoxidil intoxication, coinciding with contact with a family member using the drug, suggesting environmental exposure may trigger cardiac events in pets.
This case report details a 47-year-old female with atopic dermatitis who developed alopecia areata after six months on dupilumab therapy; treatment discontinuation and other interventions led to complete hair regrowth, suggesting dupilumab may trigger alopecia areata in patients with atopic or autoimmune predispositions.
January 2025 in “Figshare” This case report describes a 17-month-old girl who experienced sudden hair whitening during septic shock, suggesting systemic stress may trigger canities subita in young children and highlighting the need to distinguish it from congenital pigment dilution syndromes.
January 2025 in “Figshare” In this case study, a 17-month-old girl experienced sudden hair depigmentation during septic shock hospitalization, suggesting systemic stress as a potential trigger for pediatric canities subita associated with diffuse alopecia areata.
November 2024 in “PubMed” This case report describes an 18-month-old boy who developed a rare phototoxic skin reaction to terbinafine, likely triggered by sunlight exposure, which resolved after treatment with corticosteroid cream and sun avoidance.
In this case study, a 19-year-old woman with Henoch-Schönlein purpura, potentially triggered by hepatitis B vaccination, experienced improved symptoms after correcting low vitamin D levels and undergoing tonsillectomy, demonstrating these interventions may benefit similar patients.
March 2024 in “Homoeopathic links” This study reports that acute telogen effluvium, characterized by sudden hair loss occurring 2 to 3 months after a physical stressor, is not widely caused by daily life stress, with spontaneous regrowth usually happening within 3 to 6 months unless the trigger recurs.
February 2024 in “Recima21” This study explored the connections between Covid-19 and hair loss issues like telogen effluvium and alopecia areata, highlighting the virus's potential trigger effect and underscoring the importance of comprehensive post-Covid-19 treatment strategies that consider immune, psychological, and hair cycle factors.
February 2024 in “Advanced Functional Materials” This study reported that a newly developed hydrogel patch, designed to recruit regulatory T cells through ROS-triggered release of CCL22, improved wound healing and hair follicle regeneration in a diabetic mouse model by scavenging ROS, thereby protecting Tregs and suppressing Th17 cells.
January 2024 in “Wiadomości Lekarskie” In this overview of COPD exacerbations, it was reported that these events, often triggered by respiratory viruses, not only worsen symptoms but also increase the risk of cardiac events, highlighting the importance of early detection and prevention strategies such as vaccinations and new biologic therapies.
October 2023 in “Oncotarget” In this study using live mice, researchers observed that during hair follicle regression, apoptosis in basal cells may propagate by triggering neighboring cells, potentially regulated by a gradient of pro-survival signals from stem cells, and proposed a testable mechanism to further explore this process.
September 2023 in “Diagnostics” In this study, researchers found a significant relationship between mid-luteal progesterone levels and 25-hydroxy vitamin D levels in infertile patients, suggesting that about 20 ng/mL of vitamin D may be necessary to trigger ovulation or support progesterone secretion.
June 2023 in “British Journal of Dermatology” In this case series, researchers observed a rare presentation of lichen planopilaris confined to the face in six patients, with dermoscopic and histopathological profiles indicating scarring alopecia and pigment changes, and suggested that shaving and mustard oil use might trigger the condition.
May 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study explored the potential link between an increase in telogen effluvium cases and COVID-19, suggesting that the infection's trigger factors may directly influence this hair loss condition, underscoring the need for effective treatment strategies.
April 2023 in “Dermatology practical & conceptual” This study found that in female patients with COVID-19-related hair loss, diffuse hair loss and antinuclear antibody positivity might be linked to high antibody levels triggered by the infection.
April 2023 in “Journal of Investigative Dermatology” This study suggests that linalool, a common allergen in personal care products, may contribute to frontal fibrosing alopecia pathogenesis by triggering immune responses and depleting hair follicle stem cells, especially in sensitized individuals.
November 2022 in “Medicina” This case report describes post-COVID-19 telogen effluvium in a 39-year-old patient, suggesting that COVID-19 may trigger significant hair loss as a late symptom.
October 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that fly blood progenitors in a long-term organ culture model undergo symmetric cell divisions influenced by cell size and orientation, with infection triggering changes in cell differentiation kinetics.
This hypothesis paper suggests that sexual and cognitive dysfunctions reported by some men after using finasteride and dutasteride may stem from vascular and tissue changes in penile tissue triggering broader inflammatory effects.
In this study, a case of post-COVID telogen effluvium was reported in which fever and stress following COVID-19 triggered temporary hair loss, and topical treatment showed positive results in improving this condition.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This study reports two cases where lichen planus developed only in depigmented areas of vitiligo, supporting possible theories of trauma or photodamage triggering this occurrence.
January 2015 in “International Journal of Clinical & Medical Imaging” This case report describes a 63-year-old woman successfully treated for erosive pustular dermatosis of the scalp, a rare condition often triggered by trauma and misdiagnosed as other skin disorders.
January 2015 in “Rawal Medical Journal” This study found that the most common cause of diffuse hair loss in Jordanian females was telogen effluvium, often triggered by nutritional deficiencies and various forms of stress.
In this study, the n-hexane fraction of wheat bran significantly promoted hair growth in rat vibrissa follicles and triggered the telogen-anagen transition in C57BL/6 mice, likely through cell cycle and Wnt/β-catenin signaling pathways.
February 2006 in “Journal of The American Academy of Dermatology” This study found that Malassezia globosa, a scalp-associated fungus linked to dandruff, grows with saturated but not unsaturated fatty acids, potentially causing unsaturated fatty acid accumulation on the scalp and triggering dandruff-like flaking in susceptible individuals.
January 2001 in “Biomedical Research” This study observed that PAD type III and trichohyalin are expressed earlier than their deiminated form during the first and second hair cycles in rat hair follicles, indicating a potential additional factor is involved in triggering deimination.
January 2012 in “Vitamins & trace elements” This study observed that smokers and alcohol consumers with androgenetic alopecia had significantly lower serum levels of antioxidant vitamins, and these habits may trigger earlier onset of alopecia in susceptible individuals.