November 2025 in “Cosmetics” This study found that of the many ingredients advertised in shampoos as effective against hair loss, only caffeine, adenosine, placental proteins, and melatonin have limited clinical evidence supporting their efficacy, with most claimed active ingredients lacking any trial-based validation.
This study found that while many shampoo ingredients are marketed as effective against hair loss, only caffeine, adenosine, placental proteins, and melatonin have moderate clinical evidence for efficacy, and a majority of other claimed active ingredients lack clinical trial verification.
January 2024 in “Estetologia Medyczna i Kosmetologia” In this study analyzing trichological shampoos on the Polish market, researchers reported that most active ingredients claimed to combat hair loss were found in only one product each, questioning the scientific evidence supporting these claims.
4 citations
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March 2021 in “Journal of Surfactants and Detergents” This study found that hair treated with shampoo containing water-soluble silicone demonstrated smoother sliding and better detangling, compared to shampoo with water-insoluble silicone, due to differences in conditioning film formation.
March 2023 in “Aktualʹnì pitannâ farmacevtičnoï ì medičnoï nauki ta praktiki” This study found that a 2% minoxidil cream and a gel-based shampoo with 1% minoxidil plus plant extracts showed significant hair growth and follicle-protective effects in laboratory rats with experimental alopecia.
97 citations
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January 2005 in “Wear” In this study, the researchers measured and discussed the friction and wear properties of various hair types against synthetic skin and other hair, finding variations based on factors like ethnicity, hair condition, and environmental conditions.
This abstract does not report results, instead, it explores the often personal and emotional experience of noticing hair loss, noting the lack of clear medical symptoms and the potential social impact, which can lead to confusion about seeking appropriate medical care.
1 citations
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January 2026 This study outlined modern approaches for using cosmeceuticals in trichology, emphasizing evidence-based medicine, personalized care, and patient safety. It proposed the H.A.I.R. model as a universal algorithm for trichological programs and suggested new educational and practical tools for specialists in trichology and aesthetic medicine.
December 2025 in “Ekonomia/Acta Universitatis Wratislaviensis. Ekonomia” In this case study, researchers observed that demand for trichology services among customers aged 60 and older is increasing more rapidly than overall company revenue at the Hairmitage Clinic, suggesting a promising market in this demographic.
December 2025 in “Aesthetic Cosmetology and Medicine” This study emphasizes the need for personalized hair care strategies based on in-depth diagnostics, taking into account scalp type, environmental factors, and the microbiome, suggesting that this holistic approach could improve hair condition.
124 citations
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August 1990 in “British Journal of Dermatology” Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.
6 citations
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March 2019 in “JAAD case reports” This review discusses treatment strategies for alopecia areata, emphasizing current immunomodulation approaches but reports no new clinical results.
4 citations
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January 2021 in “Skin appendage disorders” This review discusses the complex causes of trichodynia and reports no clinical results; the authors call for more research into neural and immune interactions in scalp conditions.
March 2023 in “The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy” In this study, new formulations of 2% minoxidil cream and a minoxidil shampoo with plant antioxidants showed significant hair growth-stimulating and follicle-protective effects in an experimental alopecia model.
10 citations
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August 2021 in “Cosmetics” This study identified an optimal sulfate-free and silicone-free conditioning shampoo formulation using 1% hyaluronic acid at 800 kDa, 10% acidic sophorolipid, and 1% sodium chloride, which maintains essential conditioning and cleansing properties without compromising on performance.
February 2026 in “Middle European Scientific Bulletin” In this study, researchers explored the formation of the skin's epidermal barrier, its interplay with skin microbiota, and the role of skin appendages, suggesting that probiotics might offer promising avenues for treating scalp diseases, particularly those affecting hair loss.
September 2023 in “International Journal of Trichology” In this case series, the authors reported effective hair regrowth and resolution of symptoms in three pediatric patients with folliculitis decalvans following treatment with a combination of antibiotics, retinoids, dapsone, and corticosteroids.
2 citations
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July 2023 in “Cosmetics” In this study, researchers highlighted that while hair lipids are crucial for hair health and protection, surfactants in shampoos and conditioners can partially remove these lipids, potentially affecting hair structure, though the exact mechanisms remain poorly understood and require further investigation.
November 2025 in “Quality in Sport” This study reviews natural hair and scalp care methods, highlighting the importance of plant-derived ingredients and scalp type diagnostics for effective trichological management and optimal hair health.
63 citations
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October 2005 in “Archives of Dermatology” This study reports that a hair shedding threshold of 100 hairs or more may provide the best concordance with clinical diagnosis for distinguishing chronic telogen effluvium from androgenetic alopecia.
2 citations
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January 2012 in “International Journal of Trichology” Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.
4 citations
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January 2016 in “Postepy Dermatologii I Alergologii” This article discusses various hair diseases and emphasizes their significant impact despite affecting a small area, but does not report new clinical findings.
February 2026 in “American Scientific Research Journal for Engineering, Technology, and Sciences (Global Society of Scientific Research and Researchers)” This study analyzed gray hair, revealing that it differs from pigmented hair in follicular activity, oxidative balance, and structure, impacting coloring processes and necessitating adapted techniques to maintain hair quality.
35 citations
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January 1993 in “International Journal of Dermatology” In this study, most hair disorders among HIV-1 positive patients were associated with low helper T cell counts, with papulosquamous conditions like seborrheic dermatitis and psoriasis being the most common.
76 citations
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June 2008 in “Journal of the American Academy of Dermatology” In this study, key histologic features such as mucinous perifollicular fibroplasia were identified to aid in the diagnosis of lichen planopilaris.
239 citations
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July 2002 in “Clinical and Experimental Dermatology” This review explores the role of nutritional factors in hair loss, noting that iron and l-lysine supplementation may benefit some individuals, while excessive supplements can lead to hair shedding.
22 citations
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January 2017 in “Skin appendage disorders” This research analyzed 72 primary scarring alopecia cases in a Barcelona hospital, finding that the majority involved women, with a lymphocytic infiltrate and subacute onset in many cases, leading to stable disease, while neutrophilic cases had more acute episodes.
October 2025 in “International Journal For Multidisciplinary Research” This review study found strong scientific support for traditional Indian hair care practices, demonstrating that herbs like Amla, Bhringraj, and Ashwagandha have beneficial effects on hair growth and scalp health, backed by technological advancements that enhance their therapeutic potential.
In this case report, off-label onabotulinumtoxin-A was successfully used to treat trichodynia, a painful scalp sensation associated with hair loss, in a patient unresponsive to conventional therapies.
73 citations
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March 2009 in “Seminars in Cutaneous Medicine and Surgery” This article reviews various diagnostic tools for hair disorders, describing methods ranging from invasive to noninvasive, but reports no new research findings or clinical results.