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    Glossary Trichohyalin

    protein in hair follicles aiding keratin filament organization

    Trichohyalin is a protein found in hair follicles and the inner root sheath of hair. It plays a crucial role in the structural integrity and strength of hair by helping to organize and cross-link keratin filaments, which are the main structural components of hair.

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    1. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009 · 234 citations
    2. The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein Journal of Biological Chemistry · 1993 · 161 citations
    3. The Fate of Trichohyalin 1997 · 135 citations
    4. Trichohyalin, an intermediate filament-associated protein of the hair follicle. 1986 · 116 citations
    5. Trichohyalin Mechanically Strengthens the Hair Follicle 2003 · 108 citations
    6. Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes 1998 · 99 citations
    7. Analysis of the sheep trichohyalin gene: potential structural and calcium-binding roles of trichohyalin in the hair follicle. The Journal of Cell Biology · 1993 · 72 citations
    8. Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages Journal of Investigative Dermatology · 2014 · 68 citations
    9. Trichohyalin is a Potential Major Autoantigen in Human Alopecia Areata Journal of Proteome Research · 2010 · 66 citations
    10. Existence of trichohyalin-keratohyalin hybrid granules: Co-localization of two major intermediate filament-associated proteins in non-follicular epithelia Differentiation · 1994 · 54 citations
    11. Trichohyalin: Presence in the Granular Layer and Stratum Corneum of Normal Human Epidermis 1991 · 48 citations
    12. The cDNA-deduced amino acid sequence for trichohyalin, a differentiation marker in the hair follicle, contains a 23 amino acid repeat. 1990 · 39 citations
    13. Keratohyalin, Trichohyalin and Keratohyalin‐Trichohyalin Hybrid Granules: An Overview The Journal of Dermatology · 1992 · 30 citations
    14. Identification of Trichohyalin-Like 1, an S100 Fused-Type Protein Selectively Expressed in Hair Follicles Journal of Investigative Dermatology · 2011 · 27 citations
    15. Trichohyalin: A structural protein of hair, tongue, nail, and epidermis 1993 · 27 citations
    16. Immunolocalization of Scaffoldin, a Trichohyalin‐Like Protein, in the Epidermis of the Chicken Embryo The Anatomical Record · 2014 · 17 citations
    17. Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein Journal of Investigative Dermatology · 1992 · 16 citations
    18. Fine structure and immunocytochemistry of monotreme hairs, with emphasis on the inner root sheath and trichohyalin‐based cornification during hair evolution Journal of morphology · 2004 · 15 citations
    19. Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte Journal of Dermatological Science · 2011 · 12 citations
    20. Fine structure of marsupial hairs, with emphasis on trichohyalin and the structure of the inner root sheath Journal of morphology · 2004 · 8 citations
    21. Molecular elements of the regulatory control of keratin filament modulator AHF/trichohyalin in the hair follicle Experimental Dermatology · 2008 · 7 citations
    22. Cytochemistry of Trichohyalin Granules: A Possible Role for Cornification of Inner Root Sheath Cell in the Hair Follicle The Journal of Dermatology · 1989 · 4 citations
    23. Immunocytochemical Localization of Peptidylarginine Deiminase Type III, Trichohyalin and Deiminated Trichohyalin in Infant Rat Dorsal Skin Hair Follicle Biomedical Research · 2001 · 2 citations
    24. The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein 1993 · 2 citations
    25. 120 Identification of post-translationally modified trichohyalin epitopes responsible for triggering autoimmunity in alopecia areata Journal of Investigative Dermatology · 2023
    26. Trichohyalin: Purification from Porcine Tongue Epithelium and Characterization of the Native Protein 2021
    27. Morphogenesis- and Hair Cycle-dependent Expression of Trichohyalin, Peptidylarginine Deiminase Type III and Deiminated Trichohyalin in Rat Dorsal Skin Hair Follicles Biomedical Research · 2001
    28. Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21 1993
    29. Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21 Journal of Investigative Dermatology · 1993 · 37 citations
    30. Variation in the ovine trichohyalin gene and its association with wool curvature Small Ruminant Research · 2017 · 8 citations