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30-60 / 185 results![Hair, Cutaneous Homeostasis and Stem Cell Functions](/images/research/f2a7fe1a-209f-45d5-b9f9-9da0da7ecfe5/small/12835.jpg)
research Hair, Cutaneous Homeostasis and Stem Cell Functions
Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
![iPSC-based approach for human hair follicle regeneration](/images/research/242aa361-0395-45f0-b75a-9d6e19f252ac/small/11450.jpg)
research iPSC-based approach for human hair follicle regeneration
The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
![Activin A-induced signalling controls hair follicle neogenesis](/images/research/831affe7-17ca-4af4-8257-cbe8da06a8bf/small/12192.jpg)
research Activin A-induced signalling controls hair follicle neogenesis
Activin A is important for creating new hair follicles.
research Human Induced Pluripotent Stem Cell–Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo
Human stem cells can help form hair follicles in mice.
![Hair follicle regeneration from human pluripotent stem cells](/images/research/1c0f2da7-add6-4e99-bc4e-fd624132fcea/small/3979.jpg)
research Hair follicle regeneration from human pluripotent stem cells
Scientists have found a way to create hair follicles from human stem cells, which could potentially be used to treat hair loss.
![The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability](/images/research/ec3485a0-c949-4b92-9672-307bf546cd89/small/34638.jpg)
research The CD44+ALDH+ Population of Human Keratinocytes Is Enriched for Epidermal Stem Cells with Long-Term Repopulating Ability
Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
![Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells](/images/research/a485ce31-318c-422e-ab8f-02cafe9583be/small/18295.jpg)
research Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells
Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
![Hair follicle germs containing vascular endothelial cells for hair regenerative medicine](/images/research/a2185b1d-f8fb-43b8-8c0e-3b0921c44448/small/15813.jpg)
research Hair follicle germs containing vascular endothelial cells for hair regenerative medicine
Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
![Hair Growth Promoting Effect of Dermal Papilla Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells in Athymic Nude Mice](/images/research/77886b8f-04cd-4342-b271-a51c816ba1b5/small/23042.jpg)
research Hair Growth Promoting Effect of Dermal Papilla Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells in Athymic Nude Mice
Tissue from dog stem cells helped grow hair in mice.
![Hair growth promoting effect of dermal papilla like tissues from canine adipose-derived mesenchymal stem cells through vascular endothelial growth factor](/images/research/56074e8f-6d51-4630-986c-d23dce12ad83/small/23058.jpg)
research Hair growth promoting effect of dermal papilla like tissues from canine adipose-derived mesenchymal stem cells through vascular endothelial growth factor
Lab-made tissues from dog fat stem cells can help grow hair by releasing a growth factor.
![Review of hair follicle dermal cells](/images/research/acd99e47-2489-4e69-87fb-fb03843c5ba5/small/12867.jpg)
research Review of hair follicle dermal cells
Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
![Expansion Culture of Hair Follicle Stem Cells through Uniform Aggregation in Microwell Array Devices](/images/research/9a9ebd94-189e-4026-843b-71bdbc4a270d/small/16713.jpg)
research Expansion Culture of Hair Follicle Stem Cells through Uniform Aggregation in Microwell Array Devices
The new microwell device helps grow more hair stem cells that can regenerate hair.
![A model system to analyse the ability of human keratinocytes to form hair follicles](/images/research/7bd8ed30-318b-4189-b407-56f6b653a604/small/12834.jpg)
research A model system to analyse the ability of human keratinocytes to form hair follicles
Scientists developed a system to study human hair growth using skin cells, which could help understand hair development and improve skin substitutes for medical use.
![In vitro hair follicle growth model for drug testing](/images/research/08bf902a-b1de-4132-96ee-16a23af4f1da/small/16687.jpg)
research In vitro hair follicle growth model for drug testing
Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
![Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration](/images/research/001f1984-b690-4f92-a2fb-ff1734df0c7e/small/3247.jpg)
research Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration
Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
![857 Human hair follicle regeneration with trichogenic human dermal papilla precursor cells derived from induced pluripotent stem cells](/images/research/2e551550-4c14-4557-b68a-dd02590c0bef/small/4022.jpg)
research 857 Human hair follicle regeneration with trichogenic human dermal papilla precursor cells derived from induced pluripotent stem cells
Stem cells can create hair follicles, potentially treating permanent hair loss, and healthy skin and hair depend on mitochondrial function and special fats.
![Generation of trichogenic adipose-derived stem cells by expression of three factors](/images/research/ed4f4083-7b54-4dd4-aad7-5fc9ebac5a1b/small/19407.jpg)
research Generation of trichogenic adipose-derived stem cells by expression of three factors
Scientists made stem cells that can grow hair by adding three specific factors to them.
![Hypoxia inducible factor-1a promotes trichogenic gene expression in human dermal papilla cells](/images/research/ce2c6935-8187-49f8-84b0-33024fa0b252/small/16822.jpg)
research Hypoxia inducible factor-1a promotes trichogenic gene expression in human dermal papilla cells
A protein called HIF-1a helps control hair growth genes and could be targeted to treat hair loss.
![Hypoxia inducible factor-1α promotes trichogenic gene expression in human dermal papilla cells](/images/research/3b72a800-3aea-40a2-aee8-bbe5231a3517/small/16724.jpg)
research Hypoxia inducible factor-1α promotes trichogenic gene expression in human dermal papilla cells
HIF-1α is important for hair growth and could be a treatment target for hair loss.
![A Two-Stepped Culture Method for Efficient Production of Trichogenic Keratinocytes](/images/research/b4a2e181-bc9c-4ff0-9ec9-113d4075780f/small/12816.jpg)
research A Two-Stepped Culture Method for Efficient Production of Trichogenic Keratinocytes
A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
![Electrical stimulation to human dermal papilla cells for hair regenerative medicine](/images/research/b066029e-7568-42f7-bf14-38a3e18f3252/small/13069.jpg)
research Electrical stimulation to human dermal papilla cells for hair regenerative medicine
Electric stimulation can increase hair growth by activating certain genes in skin cells.
research Generation of iPS-derived model cells for analyses of hair shaft differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
![1324 Impairment of hair-inducing capacity of 3D-cultured human dermal papilla cells by the ablation of STAT5](/images/research/748de64b-45bd-43fb-a8fa-e1c316b4df6c/small/19439.jpg)
research 1324 Impairment of hair-inducing capacity of 3D-cultured human dermal papilla cells by the ablation of STAT5
Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.
![859 Building a functional niche for hair follicle stem cells](/images/research/d5634809-8a10-4203-9a11-8f1e5cdeab13/small/19537.jpg)
research 859 Building a functional niche for hair follicle stem cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
![Supplementary Material for: Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro](/images/research/ffe12a1d-28e7-47f2-a2bb-002cba795598/small/26841.jpg)
research Supplementary Material for: Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro
Metformin helps regenerate hair follicles in lab conditions.
![Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression](/images/research/a26edb69-b18b-424e-bf49-b8ae132ac6bf/small/34735.jpg)
research Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression
Chilled ATPv-supplemented saline best preserves hair grafts' key genes.
![1α,25-Dihydroxyvitamin D3 Modulates the Hair-Inductive Capacity of Dermal Papilla Cells: Therapeutic Potential for Hair Regeneration](/images/research/03b9e325-ba26-4637-b07a-83d251ff1bc5/small/12854.jpg)
research 1α,25-Dihydroxyvitamin D3 Modulates the Hair-Inductive Capacity of Dermal Papilla Cells: Therapeutic Potential for Hair Regeneration
Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
![600 Differential Molecular Signature of Dermal Papilla Cells (DPCs) from Balding and Non balding Scalp in 2D, 3D culture and Co-culture with Adipose-derived stem cells (ASCs)](/images/research/64de052b-9735-4c7c-a4b1-a375542c29fa/small/13488.jpg)
research 600 Differential Molecular Signature of Dermal Papilla Cells (DPCs) from Balding and Non balding Scalp in 2D, 3D culture and Co-culture with Adipose-derived stem cells (ASCs)
Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
![858 IPSC derived keratinocyte differentiation from reprogrammed blood cells](/images/research/ccda2d6c-2bb4-4b09-8a7b-82b5b7701213/small/19548.jpg)
research 858 IPSC derived keratinocyte differentiation from reprogrammed blood cells
Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.