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Understanding hair biology is key to developing better treatments for hair and scalp issues.

High MUC-18/MCAM levels in blood indicate a worse outlook for melanoma patients.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Androgens can both increase body hair and cause scalp hair loss.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Androgens can both increase and decrease hair growth in different parts of the body.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.

Targeting IL-17 could help treat pattern hair loss.

Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.

Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Hair proteins in preschool children and their mothers could indicate developmental changes and health status.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.