September 2021 in “VNU Journal of Science: Medical and Pharmaceutical Sciences” This review discusses the diverse applications of platelet-rich plasma (PRP) across various medical fields and reports no new clinical results, advocating PRP as a promising therapy for future use.
June 2021 in “Research Square (Research Square)” This meta-analysis reported that statins significantly reduced androgen levels and improved skin symptoms in women with polycystic ovary syndrome compared to control treatments.
June 2020 in “Dermatologic therapy” Using Janus kinase inhibitors (JAKi) in COVID-19 treatment requires careful consideration due to their immunosuppressive effects.
April 2019 in “Biometrics” This discussion reviews a hybrid phase I-II/III clinical trial design that enables dose re-optimization in phase III, but reports no new findings.
April 2018 in “Journal of Investigative Dermatology” This study suggests that for dermatomyositis patients with minimal skin disease activity, further improvement in cutaneous symptoms may not translate into better quality of life, highlighting a need to revise trial endpoints.
November 2010 in “Value in Health” Using a call center to collect data in a trial for eye disease in diabetics led to high response rates and very little missing information.
August 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This article replies to a critical appraisal of a randomized trial on melatonin in alopecia and reports no new clinical findings.
May 2015 in “Hair transplant forum international” This article discusses adverse event reporting in clinical trials of finasteride for androgenic alopecia and reports no new clinical findings.
105 citations
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January 2004 in “The Journal of Urology” This study found that finasteride significantly improved symptoms in CP/CPPS patients, except for voiding, unlike saw palmetto which showed no long-term benefits.
55 citations
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July 2020 in “International Wound Journal” This study evaluated the feasibility of a single-center, three-arm trial to assess fat grafting with or without PRP for diabetic foot ulcers, finding high patient engagement and indicating that a multi-center trial could be safe and feasible.
50 citations
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May 2000 in “Fertility and Sterility” This study found that flutamide was more effective than finasteride in reducing hair growth in women with hirsutism over a one-year period.
49 citations
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August 2009 in “British Journal of Cancer” This study observed that finasteride use among men with benign prostatic hyperplasia was associated with a decreased incidence of low-grade prostate cancer but not high-grade tumors.
47 citations
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July 2005 in “British Journal of Dermatology” This study found no protective effect of topical calcipotriol on hair loss in chemotherapy patients, and the authors propose the term "atrophic telogen effluvium" for this type of hair loss.
24 citations
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December 2020 in “Kardiologiia” This study found that combining bromhexine and spironolactone was effective in improving clinical outcomes and reducing viral load or hospitalization duration in patients with mild to moderate COVID-19.
16 citations
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January 1995 in “Dermatology” This case report discusses chronic mucocutaneous candidiasis with autoimmune and immune deficiencies in candidiasis-endocrinopathy syndrome, noting associated alopecia areata, ineffective topical immunotherapy, and asplenia.
3 citations
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November 2005 in “Journal of Research in Medical Sciences” This study found that six months of using finasteride cream 0.5% did not significantly change the number or thickness of facial hair in women with hirsutism, although patients felt hair growth slowed.
1 citations
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January 2024 in “Curēus” This case study reported significant clinical improvement in a 26-year-old male with dissecting cellulitis of the scalp after treatment with upadacitinib, suggesting that JAK inhibitors may be a promising option for refractory cases, where standard treatments have limited success.
December 2025 in “Journal of the European Academy of Dermatology and Venereology”
January 2025 in “Investigative and Clinical Urology” This study found that after 12 weeks of taking the trial product SHPro®, participants reported improvements in prostate symptom scores and erectile function, with confirmed safety.
In this study, minoxidil combined with PRP was found to effectively increase hair density in women with female pattern hair loss, but showed no superiority over minoxidil alone. No major side effects were reported.
This study reported that treating PCOS with Karunjchirakam Chooranam showed significant improvements in various cases, suggesting it may be effective for early intervention and prevention of complications.
January 2018 in “International journal of food and nutrition research” Intermittent iron and nutritional supplements can help reduce hair loss.
August 2019 in “Journal of The American Academy of Dermatology” Platelet-rich plasma helps hair regrowth and improves quality of life in women with hair loss, but minoxidil may be more effective.
165 citations
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February 1994 in “Fertility and Sterility” This study found that flutamide was more effective than spironolactone in reducing symptoms of hirsutism and related conditions in premenopausal women, with fewer discontinuations due to side effects.
121 citations
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April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.
55 citations
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June 2007 in “Journal of Statistical Planning and Inference” This study introduces an extended approach to the Bonferroni procedure that accounts for correlations among endpoints, aiming to improve test power while maintaining strong control of the family-wise type I error rate in clinical trials.
52 citations
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July 1998 in “Urology” This study found that liarozole is more effective than cyproterone acetate for improving PSA response and survival in metastatic prostate cancer after first-line endocrine therapy, while maintaining quality of life.
31 citations
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June 2018 in “Dermatologic Surgery” In this randomized, double-blind trial, researchers observed that low-level laser therapy led to significantly greater hair regrowth on treated areas compared to a sham treatment in patients with androgenetic alopecia over 24 weeks, suggesting it as a potentially effective and safe option.
25 citations
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November 2022 in “British journal of dermatology/British journal of dermatology, Supplement” In this analysis, safety data from two clinical trials showed that baricitinib for severe alopecia areata had predictable side effects like infections and elevated CPK, with some serious adverse events noted at low incidence rates; no deaths were reported.