January 2026 in “Dermatologic Therapy” This study found that combining ablative fractional CO2 laser treatment with topical minoxidil significantly improved frontal hairline regrowth and patient satisfaction in men with androgenetic alopecia compared to using minoxidil alone, without serious adverse effects.
December 2025 in “Mendeley Data” This registered trial will investigate whether preoperative botulinum toxin can improve hair transplantation outcomes by enhancing blood flow and reducing ischemia in the scalp.
November 2025 in “Frontiers in Nutrition” Olive leaf extract may help reduce aging signs in postmenopausal women.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this open-label study of post-menopausal women with frontal fibrosing alopecia, researchers found that 12 weeks of baricitinib monotherapy significantly reduced disease activity as measured by the Lichen Planopilaris Activity Index, improved patient-reported scalp hair growth, but showed no significant change in eyebrow growth.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This phase 3 trial found that over 50% of adolescents with severe alopecia areata achieved successful hair regrowth after 52 weeks on baricitinib 4-mg, with no new safety concerns reported compared to existing safety profiles.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This study evaluated the long-term safety of ritlecitinib in adolescents with alopecia areata and found it to be well-tolerated without new safety concerns over approximately five years, with common adverse events including positive SARS-CoV-2 tests, acne, headache, and nasopharyngitis.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this study, nearly one-third of patients with severe alopecia areata treated with ritlecitinib achieved complete scalp hair regrowth at least once over three years, and most maintained regrowth or stayed at low hair loss levels subsequently.
November 2025 in “SKIN The Journal of Cutaneous Medicine” In this phase 3 trial, baricitinib showed effectiveness and safety in both adolescents and adults with severe alopecia areata, with adolescents achieving higher response rates despite more severe baseline conditions, suggesting the advantages of early treatment.
November 2025 in “Journal of Multidisciplinary Healthcare” This study found that combining fire needle therapy with DHT treatment over eight weeks improved lesion severity, scar symptoms, quality of life, and reduced serum inflammatory cytokine levels in patients with moderate-to-severe acne vulgaris compared to using DHT alone.
October 2025 in “International Journal of Research in Dermatology” This clinical study found that a three-month Ayurvedic leave-on treatment significantly improved hair density and reduced hair fall in healthy Indian adults experiencing hair loss, with efficacy supported by increased VEGF expression in dermal papilla cells, promoting follicular angiogenesis.
October 2025 in “Plastic & Reconstructive Surgery” This study evaluated the safety and effectiveness of MNC-QQ cell therapy in five men with androgenic alopecia, reporting no adverse effects and improvements in hair growth, hair density, and quality of life over six months.
October 2025 in “Dermatology and Therapy” This study evaluates the efficacy and safety of a higher dose (100-mg) of ritlecitinib for treating severe alopecia areata, comparing it to external and synthetic placebo control groups.
September 2025 in “Journal of Pakistan Association of Dermatologists” This study compared the effectiveness of adding Biotin supplements to PRP treatment against using PRP alone for androgenetic alopecia patients and found no additional benefits in hair regrowth when Biotin was included.
September 2025 in “Journal of Pakistan Association of Dermatologists” This randomized controlled trial reported that combining oral Biotin supplements with PRP offered no additional benefits for hair regrowth in patients with Androgenetic Alopecia compared to PRP alone.
September 2025 in “Dermatologic Surgery” This study found that combining Fractional Microneedling Radiofrequency (FMRF) with topical minoxidil significantly increased hair counts and density more than minoxidil alone or combined with Fractional CO2 in women with androgenic alopecia.
September 2025 in “Journal of Cosmetic Dermatology” This study found that both PRP injections and microneedling treatments significantly improved hair count and thickness in patients with androgenetic alopecia, without significant differences between the two methods. Microneedling also enhanced patient satisfaction and treatment tolerance.
September 2025 in “Journal of the American Academy of Dermatology” Combining minoxidil and PRP is more effective for hair growth than using either alone.
September 2025 in “Journal of the American Academy of Dermatology” Deuruxolitinib significantly improves hair satisfaction in severe alopecia areata patients.
August 2025 in “Lasers in Medical Science” In this study, the combination of low-level laser therapy and topical minoxidil was found to improve hair density and diameter more effectively than minoxidil alone in treating androgenic alopecia, with similar safety profiles observed in both groups.
This study concluded that adding a topical agent to intense pulsed light therapy significantly improved hair reduction and patient satisfaction in Pakistani women with idiopathic facial hirsutism compared to light therapy alone, without increasing adverse effects.
August 2025 in “International Journal of Ayurveda360” In this randomized controlled trial, the combination of Bhringaraja Taila Shiroabhyanga and Yastimadhuka Taila Nasya was found to significantly improve hair density, reduce hair fall, and decrease scalp visibility in females with Khalitya compared to Nasya alone, with no reported adverse effects.
August 2025 in “Indian Dermatology Online Journal” In this study, both methotrexate gel and betamethasone lotion were found to be effective and safe treatments for localized alopecia areata, with similar overall response rates. However, methotrexate gel had a higher incidence of local side effects, such as irritant dermatitis and itching.
August 2025 in “Indian Dermatology Online Journal” This study found that combining topical minoxidil with phototherapy significantly improved pigmentation and reduced vitiligo severity compared to placebo, as measured by VASI scores over 12 weeks, though the sample size was small and follow-up short.
August 2025 in “BMJ Open” In this randomized controlled trial, researchers are assessing the efficacy and safety of acupoint catgut embedding combined with topical 5% minoxidil in treating androgenetic alopecia among 70 men, with primary outcomes focusing on changes in hair count after 24 weeks of treatment.
July 2025 in “SKIN The Journal of Cutaneous Medicine” This study reported that ritlecitinib was generally well tolerated over 72 months in patients aged 12 and older with alopecia areata, with adverse events like headache and nasopharyngitis observed, and safety outcomes consistent with previous studies.
June 2025 in “British Journal of Dermatology” This study compared oral tofacitinib and methotrexate in treating moderate-to-severe alopecia areata, finding that tofacitinib was more effective at reducing SALT scores and improving scalp hair assessment PRO scores, though both treatments reduced psychological distress similarly without serious adverse effects.
June 2025 in “British Journal of Dermatology” This study found that both tofacitinib and methotrexate effectively reduced hair loss and psychological distress in patients with moderate-to-severe alopecia areata, but tofacitinib showed much greater efficacy. Both treatments had similar safety profiles, with no serious adverse effects reported.
June 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology” This literature review reports that certain herbal remedies, such as rosemary, green tea, and ginseng, have shown promise in promoting hair growth and improving hair density, though variability and study design limitations highlight the need for more rigorous research.
In this clinical trial, rosemary-lavender and rosemary-castor oils were found to significantly improve hair growth rate, thickness, density, length, and reduce hair fall compared to coconut oil over 90 days, indicating they may be effective natural alternatives for hair regrowth.
May 2025 in “Actas Dermo-Sifiliográficas” The study did not find evidence to support using botulinum toxin as a treatment for androgenetic alopecia.