101 citations
,
March 2019 in “Cell Stem Cell” This study found that Oncostatin M, via JAK-STAT5 signaling, keeps hair follicle stem cells inactive, and its removal leads to hair growth initiation in mice.
62 citations
,
July 2022 in “Science Immunology” This study discovered that TREM2 macrophages influenced by squalene play a role in acne's development by hindering the killing of Cutibacterium acnes, helping explain why benzoyl peroxide is effective in treatment.
4 citations
,
April 2019 in “Cell Stem Cell” This study found that a specific macrophage subpopulation in the dermis helps maintain hair follicle stem cell quiescence through cytokine-mediated signaling.
1 citations
,
January 2012 in “Jounal of The Korean Society of cosmetology” Tremella fuciformis Berk helps protect hair from stress-related damage.
January 2026 in “Advanced Healthcare Materials” This study developed a 3D-printed scaffold for diabetic wound repair, which showed potential in a mouse model by reducing inflammation, promoting blood vessel regeneration, enhancing skin hydration, and accelerating wound healing through nitric oxide and gallium ion release, oxidative stress modulation, and antioxidant pathway activation.
March 2025 in “Stem Cell Research & Therapy” This study found that microneedles containing magnetic intracellular vesicles and tremella polysaccharide improved the hair microenvironment and accelerated hair regeneration in mice with androgenic alopecia.
April 2023 in “Journal of Investigative Dermatology” This study found that human TMEM2 does not function as a hyaluronidase but is involved in regulating hyaluronan metabolism.
October 2012 in “한국미용학회지” This study reported that stress in early life negatively impacted hair growth in mice at older ages, while Tremella fuciformis Berk extracts partially protected against these effects.
294 citations
,
February 1994 in “PubMed” This review highlights valproic acid's efficacy and tolerability as a first-line treatment for various seizure types in both adults and children, emphasizing its minimal neurological adverse effects compared to other antiepileptic drugs.
55 citations
,
December 1983 in “Acta Neurologica Scandinavica” This review discusses the side effects of carbamazepine, valproate, and clonazepam, noting that these are rare with long-term use but more common, transient, and generally mild during early treatment.
11 citations
,
January 2016 in “Bipolar Disorder” This article reviews the uses, mechanisms, and side effects of valproate in treating bipolar disorder, noting its first-line status for several manic conditions but also highlighting serious risks such as fetal abnormalities.
7 citations
,
September 2007 This study found that valproate sustained-release monotherapy provided effective short-term seizure control and was well tolerated in newly-diagnosed epileptic patients with partial seizures in the Gulf Cooperation Council countries.
6 citations
,
April 2019 in “Pesquisa Veterinária Brasileira” This article reviews the potential risks of various phytotoxins in milk for animals and humans, discussing the need for awareness and further research but providing no new findings.
4 citations
,
August 2025 in “Journal of Food Science” This review highlights that Tremella fuciformis polysaccharide exhibits various bioactivities, such as antioxidant and immune-modulating effects, and explores its potential applications in food, pharmaceutical, and cosmetic industries.
September 2024 in “Cureus” This case report describes how changing treatment from adalimumab to guselkumab successfully controlled both pustulotic arthro-osteitis and paradoxical skin reactions in a patient with palmoplantar pustulosis.
16 citations
,
February 2009 in “Clinical neurology and neurosurgery” In this study, patients with epilepsy who switched from immediate-release to extended-release divalproex sodium did not experience significant changes in seizure frequency, but most preferred the new formulation due to a subjective decrease in tremor during daily activities.
13 citations
,
October 2010 in “Seizure” This study reported that extended-release valproate significantly reduced seizure frequency and improved quality of life in epilepsy patients over six months, despite some adverse effects like weight gain and tremor.
5 citations
,
January 2017 in “Nevrologiâ, nejropsihiatriâ, psihosomatika” In this study, sustained-release sodium valproate showed high efficacy in achieving seizure remission for adults with focal and generalized epilepsy over one year, but side effects like weight gain and tremor were more frequent among heterozygous carriers of certain gene variants.
January 2004 in “Headache” This study found that two-thirds of patients with persistent chronic daily headache showed significant improvement with divalproex sodium treatment, although common side effects included weight gain, tremor, hair loss, and nausea.
111 citations
,
February 1991 in “Headache The Journal of Head and Face Pain” In this study, two-thirds of patients with persistent chronic daily headache significantly improved with divalproex sodium treatment, while liver functions remained unaffected.
64 citations
,
March 1989 in “PubMed” This review discusses the development of valproate as an effective monotherapy for controlling generalized seizures and reports no new clinical results.
60 citations
,
February 2003 in “Postgraduate Medical Journal” In this report, it was noted that severe paresthesia, ophthalmoplegia, cerebellar and extrapyramidal signs, and alopecia can strongly indicate thallium poisoning, and haemodialysis may be beneficial even in the third week after poisoning.
35 citations
,
August 2004 in “Epilepsy & behavior” In this study, divalproex sodium extended-release was found to be more tolerable and preferred by patients compared to the delayed-release formulation, with improved seizure control and psychiatric symptom relief.
21 citations
,
April 2011 in “Epilepsia” This open-label study suggests that combining valproate, lamotrigine, and a benzodiazepine can significantly reduce the frequency of epileptic drop attacks in patients with generalized or multifocal epilepsies.
16 citations
,
October 1994 in “PubMed” This review, drawing on literature and personal experience, suggests that sodium valproate is a safe and effective antiepileptic drug for various epileptic conditions in children and adults, including the elderly.
3 citations
,
November 2019 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience” Valproate can cause both hair loss and curly hair in bipolar disorder patients.
2 citations
,
July 2020 in “International journal of regenerative medicine” This study suggests that autologous fat transfer can significantly enhance hair growth in patients with scarring alopecia, offering more consistent and predictable results when combined with hair transplantation.
1 citations
,
September 2007 in “European journal of paediatric neurology” Low dose valproic acid treatment caused hair loss in a young patient.
January 2024 in “Wiadomości Lekarskie” This review outlines the evolution and impact of robotic surgery, highlighting past milestones like the da Vinci system’s prominence in prostatectomies and future advances in augmented reality and micro-robotics, while emphasizing that the surgeon's expertise remains essential despite technological progress.
December 2023 in “PubMed” This study found that both single- and double-spin PRP preparation methods significantly increased thrombocyte counts and improved hair parameters in males with androgenetic alopecia, with the single-spin method showing a more significant increase in thrombocyte count.