53 citations
,
August 2019 in “American journal of human genetics” This study found that FOXN1 haploinsufficiency is a significant genetic factor causing T cell lymphopenia at birth, linked to reduced thymic function in both humans and mice.
130 citations
,
November 2017 in “Frontiers in Immunology” This review explores recent findings on regulatory T cells, focusing on their unique functions in non-lymphoid tissues and new mechanisms of action, but presents no original clinical results.
39 citations
,
May 2014 in “Frontiers in Pharmacology” In this study, CD4+CD25+FoxP3+ Regulatory T cells were found to reduce TGF-b1 induced lung fibrosis and fibrocyte accumulation in mice, partly by suppressing fibroblast growth factor 9.
5 citations
,
June 2022 in “Frontiers in immunology” This study observed that expanding regulatory T cells in the skin of mice with alopecia areata did not reverse the condition, indicating that additional immunotherapy may be necessary.
1 citations
,
January 2023 in “International Journal of Molecular Sciences” This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.
November 2025 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study identified elevated CD25 on secreting CD4 regulatory T cells as a genetic risk factor for androgenetic alopecia, with certain plasma proteins acting as mediators in this causal relationship.
June 2024 in “Research Square (Research Square)” This study demonstrated that in mice, the absence of Jagged-1 expression in skin-resident regulatory T cells significantly delays wound healing by reducing the accumulation of neutrophils, highlighting the role of Jagged-1 in coordinating immune cell recruitment during injury.
In this study, researchers identified IL18R+ thymus-resident regulatory T cells in mice, demonstrating their unique molecular features and resistance to age- and stress-induced thymus involution, highlighting IL18 signaling's role in Treg migration and retention.
3 citations
,
January 1988
September 2016 in “Medical Journal of Australia” Planting trees and doing yoga might make you feel better; yoga can help with asthma symptoms, and certain treatments can improve female hair loss.
14 citations
,
June 2024 in “Food Chemistry X” This review highlights that pomegranate leaf exhibits potential health benefits, such as anti-cancer, anti-diabetic, anti-inflammatory, and neuroprotective effects in vitro and in animal models, but calls for comprehensive human clinical trials to confirm these therapeutic benefits and ensure safety.
8 citations
,
July 2022 in “Chinese Journal of Integrative Medicine” This review discusses the molecular phylogeny, chemical constituents, and therapeutic applications of medicinal plants in the Ranunculales order and reports no new clinical results.
5 citations
,
January 2021 in “Pakistan Journal of Nematology” This review discusses the potential of Citrullus colocynthis as a natural nematicidal agent and highlights its phytochemical composition, but reports no new experimental results.
5 citations
,
July 2019 in “Applied statistics/Journal of the Royal Statistical Society. Series C, Applied statistics” In this study, applying case-only trees and random forests to a prostate cancer prevention trial revealed genotypes that may influence the efficacy of finasteride for prostate cancer prevention.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract discusses the cosmetic and potential hair growth benefits of almond oil but presents no new empirical research findings.
June 2026 in “Journal of Investigative Dermatology”
November 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that specific immune cell phenotypes, particularly CD25 on CD4 Treg cells, were causally linked to androgenic alopecia, suggesting potential targets for immune-based therapies.
March 2025 in “Journal of Neonatal Surgery” This review focuses on the significant pharmacological properties and therapeutic potential of phytosterols, terpenoids, flavonoids, and phenolic compounds from the endangered plant Nardostachys Jatamansi, highlighting their diverse applications in disease prevention and treatment.
63 citations
,
September 2021 in “Journal of Fungi” In this review, the authors highlighted the broad range of therapeutic and health benefits of mushrooms, including antiviral, antibacterial, anticancer, and other protective effects, due to their complex chemical components like polysaccharides and glucans.
4 citations
,
February 2017 in “Journal of Cutaneous Medicine and Surgery” This study assessed the dermatologic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce used in First Nations medicine, highlighting several active compounds relevant to dermatology, but noted a lack of high-quality evidence in existing research.
January 2026 in “RSC Medicinal Chemistry” This review highlights advancements in the synthesis and biological applications of 2,5-Diazabicyclo[2.2.1]heptane, a scaffold in medicinal chemistry, focusing on its construction strategies and potential use in treatments for cancer, neurological disorders, and infections.
This review suggests that the inner root sheath of human hair follicles may have broader regulatory roles beyond structural support, potentially impacting processes like folliculogenesis, anagen phase regulation, and immunomodulation.
December 2023 in “FUDMA Journal of Sciences” In this study, researchers analyzed Vachellia nilotica and Senegalia ataxacantha from Katsina state, Nigeria, identifying various bioactive compounds in their shoots and suggesting their potential as raw materials for pharmaceutical antifungal therapies.
This study found that IL18 signaling plays a crucial role in the homing and retention of mature regulatory T cells in the mouse thymus, primarily by upregulating the chemokine receptor CCR6.
February 2019 in “Journal of the Faculty of Agriculture Kyushu University” This study found that terpene compound concentrations in coniferous tree leaves were generally highest in spring and summer, suggesting these seasons are most effective for extracting essential oils.
8 citations
,
April 2008 in “The Journal of Urology” This commentary discusses the public health implications of benign prostatic hyperplasia (BPH) and provides no new research results.
July 2024 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study observed that while anomalous adipose tissue and displaced eccrine glands were common in certain types of scarring alopecia, these findings did not assist in diagnosis.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” This study found that extracts from Geranium pyrenaicum show promising antioxidant, enzyme inhibitory, and antiviral activities, particularly the methanolic extract's antiviral activity against HSV-1.
365 citations
,
November 2018 in “Journal of Allergy and Clinical Immunology” This review discusses the role of the skin microbiome in maintaining health and modulating atopic dermatitis, emphasizing the need for novel therapeutic strategies, but reports no new clinical results.
273 citations
,
July 2020 in “British Journal of Dermatology” This review discusses recent insights into the role of regulatory T cells in psoriasis and the impact of current treatments on their function, but reports no new research findings.