Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study engineered a bioluminescent yeast strain responsive to androgenic chemicals, demonstrating rapid and sensitive detection suitable for high-throughput screening and environmental monitoring.

This study developed a closed-loop system for emergency wound care that monitors infection in real-time using biomarkers and delivers amikacin-loaded liposomes for treatment, integrating a conductive hydrogel for environmental protection and antibacterial benefits.

This study found that controlled release of hIGF-1 from TF/hIGF-1 effectively enhanced re-epithelialization and granulation tissue formation in diabetic wounds in animal models compared to controls, suggesting a promising approach for diabetic wound treatment.

This study describes the use of a genetically engineered mouse model, mTurquoise2-Col4a1, to fluorescently label collagen IV and observe basement membrane dynamics during skin development, revealing its stability and pliability during rapid growth phases.

This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.

In laboratory studies on mice, Abstract UT-018, a stem cell chemoattractant formulation, was reported to significantly enhance wound healing and promote hair regeneration through mechanisms involving improved tissue formation, collagen organization, and follicular development.

In this study, the researchers used the dual-flow-RootChip to show that Arabidopsis roots can locally adapt their hair development in response to asymmetric phosphate conditions.

This study reported successful recovery of biologically active recombinant murine Wnt3a without detergent, suggesting usefulness for structure-activity studies avoiding detergent-related issues.

This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.

This study reported that a Megsin-Cre transgene enables genetic manipulation primarily in skin, forestomach, and esophagus tissues, offering a new tool for studying development and diseases in these areas.

This study developed a nanofiber wound dressing combining ciprofloxacin and tetracycline hydrochloride, which demonstrated strong antibacterial activity against E. coli and S. aureus and showed good biocompatibility with human skin fibroblast cells, indicating significant potential for wound healing applications.

This study found that fibronectin-attached cell sheets significantly improved wound healing in vivo by increasing wound closure rates, reducing inflammation, and promoting tissue regeneration compared to conventional cell sheets.

The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.

In this study, ethosomes were found to significantly enhance the transdermal penetration and skin accumulation of finasteride compared to liposomes and other control solutions.

This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.

In this study, researchers developed a method to create skin organoids using spinning bioreactors, facilitating efficient high-throughput drug screening, and found that Minoxidil activates the Wnt/beta-catenin signaling pathway in these models.

This study developed and tested continuous implanters for dermal papilla cell aggregates, finding that the bar-cartridge type implanter is the most effective design for continuous cell implantation in androgenetic alopecia research.

This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.

In this study, FITC-labeled BSA nanocarriers delivered a model drug deeper into porcine ear skin hair follicles than the carriers themselves, as shown by confocal microscopy.

This study found that matriptase, a membrane serine protease, is crucial for maintaining multiple types of epithelial tissues in mice, with its absence leading to severe organ dysfunction and increased permeability.

The nanoemulsion system effectively delivers drugs through the skin and shows promise for treating skin conditions.

Zebrafish skin regeneration relies on cell behaviors and reactive oxygen species, with antioxidants reducing and hydrogen peroxide increasing regeneration.

This study developed a bilayer material combining poly(vinyl alcohol) and bacterial cellulose with a gelatin-poly(vinyl alcohol) hydrogel, showing strong potential as a wound dressing due to its good antibacterial properties, cell viability, and sustained drug release.

This study demonstrated that a single multimode fiber can be used for single-shot wide-field reflectance imaging, achieving high correlation with the ground truth and enabling real-time microendoscopy at up to 180 frames per second.

This study describes a new intravital microscopy method for observing intestinal regeneration by tracking crypt dynamics in living mice after laser-induced tissue damage, revealing events like crypt fission, fusion, and disappearance over multiple weeks.

This study found that KY19382, a small molecule activating the Wnt/β-catenin pathway, significantly improved wound healing by enhancing cell migration, increasing collagen and stem cell markers, and accelerating re-epithelialization and neo-epidermis formation in a murine model without causing significant cytotoxicity.

This study found that invasomes enhanced the iontophoretic transdermal delivery of finasteride in rabbits, increasing AUC and T1/2 compared to oral suspension.

This article reviews methods such as stem cell implantation to enhance hair transplant donor supply but reports no new clinical findings.