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This study optimized efinaconazole spanlastic nanovesicles using risk management and multivariate analysis for potential transungual delivery to treat onychomycosis, achieving improved drug permeability and dissolution efficiency.

Smart microneedles using advanced tech could improve psoriasis treatment.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

This study reports that fluconazole emulgel formulations, using jojoba oil and liquid paraffin, showed effective drug release and improved characteristics for treating skin diseases compared to traditional oral formulations.

This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.

This review discusses alopecia, its pathophysiology, nanotechnology-based drug delivery systems, and related quality of life issues, without reporting new clinical results.

This review outlines the potential of nanoemulsion-based hydrogels (nanoemulgels) for enhanced topical and transdermal drug delivery in treating skin disorders, highlighting their ability to improve therapeutic efficacy, control drug release, and boost patient compliance.

This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.

This source describes the potential benefits of a nanoemulgel delivery system for enhancing the use of lipophilic drugs, improving patient compliance, and expanding treatment options for various conditions, including acne, arthritis-related inflammation, and Parkinson's disease, while also offering sunburn protection in cosmetic applications.

This review examines liposome-based cosmeceuticals for various skin conditions and reports no new clinical results, highlighting the potential promise these formulations offer for future applications.

This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.

In this study, researchers developed an in-situ gel formulation of antibacterial Levofloxacin for the eye, which showed prolonged drug release, increased residence time, and effective antibacterial action, suggesting it may be a safe and effective ocular delivery system for antibiotics.

This study reported that meloxicam-loaded spanlastics, created using the ethanol injection method, demonstrated potential as a drug delivery system with sustained release and effective entrapment efficiency.

This review discusses the developments in antifungal treatments for dermatophyte infections since 2008, reporting no new oral agents but introducing newer topical options like efinaconazole and tavaborole.

This study found that Brigatinib-loaded nanospanlastics demonstrated enhanced cytotoxicity against lung cancer cells and improved drug stability and release compared to free Brigatinib.

This review found topical ketoconazole to be highly effective against Malassezia-related skin conditions, though other treatments may outperform it for Tinea and Candida infections.

This article reviews EU cosmetic product claim regulations and highlights increased harmonization and enforcement while reporting no new results.

The document lists various dermatology topics, treatments, and diagnostic methods.

This study found that keratin films made from human hair can potentially substitute for human nail plates in drug permeability studies, but they show higher sensitivity to penetration enhancers compared to bovine hooves.

This review discusses drug repurposing for various conditions, including cancer and COVID-19, highlighting ongoing trials with potential repurposed drugs but provides no new clinical results.

Transethosomes improve drug delivery through the skin and show promise for treating various conditions.

This article reviews potential applications and challenges of using the transfollicular route for drug delivery but does not present new clinical findings; it calls for further exploration and development in this field.

This review discusses ethanol-based transethosome vesicles for drug delivery through the skin, but reports no new clinical results.

Transfollicular drug delivery can improve medication absorption through hair follicles.

This review highlights that transferosomes, or ultradeformable lipids, show promise for improving dermal delivery, exhibiting efficient drug transport across the skin's barrier and offering potential benefits for treating chronic skin disorders with better bioavailability.

This article explains the preparation methods and applications for various vesicle and particle systems used in transdermal drug delivery, highlighting their effectiveness and potential for further development in this field.

This study found that invasomes enhanced the iontophoretic transdermal delivery of finasteride in rabbits, increasing AUC and T1/2 compared to oral suspension.

This review highlights that the combination of ultrasound and microneedles can enhance transdermal drug delivery by using physical and energy-driven mechanisms to improve drug penetration into deeper skin layers, with implications for precision medicine and chronic disease treatments.

This review examines ultrasound-assisted and laser-based transdermal drug delivery technologies, highlighting their success in enhancing drug penetration through the skin but also noting challenges such as parameter optimization, potential skin irritation, and high equipment costs.